Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | F7 | P08709 | 3/20 | 0.38 |
| ▸ | F3 | P13726 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479434 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL2882121 | 0.77 | ALDH1A1 (0.48) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL623306 | 0.74 | GGT1 (0.41) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL599740 | 0.74 | GGT1 (0.41) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL14557635 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL476237 | 0.73 | — | — | |
| SCHEMBL3270986 | 0.71 | ALDH1A1 (0.38) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL8743592 | 0.71 | ALDH1A1 (0.38) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL2882413 | 0.71 | ALDH1A1 (0.47) | ALDH1A1CYP19A1OXER1MAPTPPARG | |
| SCHEMBL1732575 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7771740-B2 | Medical devices containing copolymers with graft copolymer endblocks for drug delivery | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| EP-1771218-A2 | MEDICAL DEVICES CONTAINING COPOLYMERS WITH GRAFT COPOLYMER ENDBLOCKS FOR DRUG DELIVERY | Boston Scientific Scimed, Inc. (US) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006014606-A2 | MEDICAL DEVICES CONTAINING COPOLYMERS WITH GRAFT COPOLYMER ENDBLOCKS FOR DRUG DELIVERY | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2006-02-09 | — | — | WO | disclosed |
| US-20060013854-A1 | Medical devices containing copolymers with graft copolymer endblocks for drug delivery | BOSTON SCIENTIFIC SCIMED, INC. | 2006-01-19 | — | — | US | disclosed |