Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480360 | 0.94 | EPHX2 (0.31) | EPHX2XDHMCHR1 | |
| SCHEMBL3480318 | 0.84 | XDH (0.33) | XDHMCHR1 | |
| SCHEMBL3480426 | 0.84 | PTGDR (0.32) | EPHX2 | |
| SCHEMBL4002287 | 0.83 | PDE4A (0.32) | ALPLEPHX2 | |
| SCHEMBL3480294 | 0.82 | XDH (0.35) | XDH | |
| SCHEMBL13021921 | 0.82 | TRPV4 (0.32) | XDH | |
| SCHEMBL12979721 | 0.80 | AR (0.33) | — | |
| SCHEMBL12979512 | 0.80 | XDH (0.33) | XDHMCHR1 | |
| SCHEMBL3480317 | 0.79 | XDH (0.33) | XDHMCHR1 | |
| SCHEMBL3480325 | 0.79 | XDH (0.39) | XDHMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317625-A1 | NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE | 92229129 QUEBEC INC. (CA) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317625-A1 | NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE | MGAM, BPGM, PPME1 | ALPL 56/4885EPHX2 2318/4885XDH 982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.