Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 12/20 | 0.36 |
| ▸ | GABRD | O14764 | 12/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 12/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 12/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 12/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 12/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 12/20 | 0.36 |
| ▸ | GABRE | P78334 | 12/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 12/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 12/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 12/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 12/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480543 | 0.86 | DDR1 (0.41) | DDR1PDE2AGABRPGABRDGABRA1 | |
| SCHEMBL3480812 | 0.85 | GABRP (0.39) | PDE2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3480600 | 0.85 | DDR1 (0.41) | DDR1PDE2AGABRPGABRDGABRA1 | |
| SCHEMBL3480522 | 0.82 | DDR1 (0.41) | DDR1PDE2AGABRPGABRDGABRA1 | |
| SCHEMBL3480527 | 0.81 | TDP1 (0.44) | DDR1 | |
| SCHEMBL3480558 | 0.76 | GABRA2 (0.40) | DDR1PDE2AGABRPGABRDGABRA1 | |
| SCHEMBL5961599 | 0.73 | GABRP (0.37) | PDE2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3480563 | 0.72 | GABRP (0.53) | PDE2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL5961600 | 0.71 | GABRP (0.35) | PDE2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3480805 | 0.70 | MCL1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767626-B2 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-7612105-B2 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| US-20090170883-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-07-02 | — | — | US | disclosed |
| EP-1076053-B1 | 3-ARYLPHENYL SULFIDE DERIVATIVES AND INSECTICIDES AND MITICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-7037930-B2 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20050171097-A1 | 3-Arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-08-04 | — | — | US | disclosed |
| US-20050107383-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-05-19 | — | — | US | disclosed |
| US-6858639-B2 | 3-Arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-02-22 | — | — | US | disclosed |
| US-20030069242-A1 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-04-10 | — | — | US | disclosed |
| US-6509354-B1 | Insecticides and miticides containing the 3-arylphenyl sulfide derivatives as an active ingredient. | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |
| EP-1076053-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVES AND INSECTICIDES AND MITICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170883-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | CBR3, MSRB3, CYP1B1 | DDR1 1843/4885PDE2A 3449/4885GABRP 2421/4885 |
| US-20030069242-A1 | 3-arylphenyl sulfide derivative and insecticide and miticide | CYP1B1, CYP2B6, CBR3 | DDR1 1237/4885PDE2A 2453/4885GABRP 2277/4885 |
| US-20050171097-A1 | 3-Arylphenyl sulfide derivative and insecticide and miticide | CBR3, MSRB3, CYP1B1 | DDR1 1843/4885PDE2A 3449/4885GABRP 2421/4885 |
| US-20050107383-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | CBR3, MSRB3, CYP1B1 | DDR1 1843/4885PDE2A 3449/4885GABRP 2421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.