Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 14/20 | 0.37 |
| ▸ | GABRD | O14764 | 14/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 14/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 14/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 14/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 14/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 14/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 14/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 14/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 14/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 14/20 | 0.37 |
| ▸ | GABRE | P78334 | 14/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 14/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 14/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 14/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 14/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405865 | 0.84 | GABRP (0.34) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5961600 | 0.84 | GABRP (0.35) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5961593 | 0.79 | TDP1 (0.44) | — | |
| SCHEMBL3480812 | 0.78 | GABRP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5961618 | 0.77 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3480805 | 0.74 | MCL1 (0.41) | — | |
| SCHEMBL3480609 | 0.73 | DDR1 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3480563 | 0.73 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6405867 | 0.71 | NOTUM (0.34) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3480544 | 0.68 | GABRA2 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037930-B2 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20050107383-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-05-19 | — | — | US | disclosed |
| US-6509354-B1 | Insecticides and miticides containing the 3-arylphenyl sulfide derivatives as an active ingredient. | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107383-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | CBR3, MSRB3, CYP1B1 | GABRP 2421/4885GABRD 1442/4885GABRA1 2290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.