Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4392339 | 0.92 | KIF11 (0.48) | TYRMGLLCYP2C9CYP2D6HIF1A | |
| SCHEMBL104124 | 0.83 | TYR (0.58) | TYRMGLLCYP2C9CYP2D6HIF1A | |
| SCHEMBL28912214 | 0.79 | TYR (0.55) | TYRMGLLCYP2C9CYP2D6HIF1A | |
| SCHEMBL6203905 | 0.79 | TYR (0.55) | TYRMGLLCYP2C9CYP2D6HIF1A | |
| Water SCHEMBL11726962 | 0.79 | TYR (0.55) | TYRMGLLCYP2C9CYP2D6HIF1A | |
| Ammonia Solution, Strong SCHEMBL7550588 | 0.79 | TYR (0.55) | TYRMGLLCYP2C9CYP2D6HIF1A | |
| Water SCHEMBL29278796 | 0.79 | TYR (0.55) | TYRMGLLCYP2C9CYP2D6HIF1A | |
| SCHEMBL2644236 | 0.77 | NOS3 (0.45) | TYRCYP2C9CYP2D6HIF1AKDM4E | |
| SCHEMBL20474589 | 0.77 | PGK1 (0.33) | TYR | |
| SCHEMBL2643071 | 0.77 | ADRB2 (0.56) | TYRHIF1AKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 744 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683872-B | Antibacterial compostable degradable breathable film and preparation method and application thereof | 合诚技术股份有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-107337702-B | Crystal type HCV inhibitor and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2021-11-05 | — | — | CN | claimed |
| US-20180244611-A1 | Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use | ABBVIE S.Á.R.L. (LU) | 2018-08-30 | — | — | US | claimed |
| WO-2018154519-A1 | MODULATORS OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR PROTEIN AND METHODS OF USE | AbbVie S.à.r.l. (LU) | 2018-08-30 | — | — | WO | claimed |
| CN-107922945-A | LNA G methods | 罗氏创新中心哥本哈根有限公司 | 2018-04-17 | — | — | CN | claimed |
| US-7842744-B2 | excellent in ultraviolet absorption capability at 380 nm with little bleed-out; resin and an absorber, which is a tris/2-hydroxyphenyl/ triazine compound | ADEKA CORPORATION (JP) | 2010-11-30 | — | — | US | claimed |
| CN-101045805-B | Polypropylene resin composite for filling hollow shaping product and preparation method thereof | GUANGZHOU HECHENG CHEMICAL CO LTD | 2010-08-04 | — | — | CN | claimed |
| CN-101250302-B | Anti-static polyolefin ventilated membrane composition and method for preparing the same | GUANGZHOU HONSEA CHEMICAL CO LTD | 2010-06-23 | — | — | CN | claimed |
| US-20090258976-A1 | excellent in ultraviolet absorption capability at 380 nm with little bleed-out; resin and an absorber, which is a tris/2-hydroxyphenyl/ triazine compound | NEGISHI YOSHINORI | 2009-10-15 | — | — | US | claimed |
| US-7553892-B2 | excellent in ultraviolet absorption capability at 380 nm with little bleed-out; resin and an absorber, which is a tris/2-hydroxyphenyl/ triazine compound | ADEKA CORPORATION (JP) | 2009-06-30 | — | — | US | claimed |
| EP-1115693-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | Monsanto Company (US) | 2001-07-18 | — | — | EP | claimed |
| EP-1115695-A1 | (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(N+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | Monsanto Company (US) | 2001-07-18 | — | — | EP | claimed |
| EP-1115694-A1 | SUBSTITUTED N-ALIPHATIC-N-AROMATIC (TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | Monsanto Company (US) | 2001-07-18 | — | — | EP | claimed |
| EP-1042290-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-10-11 | — | — | EP | claimed |
| WO-2000050396-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-08-31 | — | — | WO | claimed |
| EP-1026149-A1 | AMIDOCARBOXYLIC ACID DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-09 | — | — | EP | claimed |
| WO-2000018724-A1 | (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(n+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | claimed |
| WO-2000018723-A1 | SUBSTITUTED N-ALIPHATIC-N-AROMATIC TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | claimed |
| WO-2000018721-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | claimed |
| WO-1999025687-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 1999-05-27 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180244611-A1 | Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use | CFTR, CLCN2, SCNN1G | TYR 4884/4885MGLL 1484/4885CYP2C9 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.