Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480041 | 1.00 | TRPV4 (0.35) | TRPV4SLC22A12 | |
| SCHEMBL3480751 | 0.93 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL3480039 | 0.93 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL14943073 | 0.92 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL14943083 | 0.91 | TRPV4 (0.36) | TRPV4 | |
| SCHEMBL14931309 | 0.88 | SLC22A12 (0.33) | TRPV4SLC22A12 | |
| SCHEMBL14931315 | 0.88 | SLC22A12 (0.33) | TRPV4SLC22A12 | |
| SCHEMBL13031985 | 0.87 | TRPV4 (0.36) | TRPV4 | |
| SCHEMBL14943080 | 0.85 | ALDH1A1 (0.36) | TRPV4 | |
| SCHEMBL14943081 | 0.85 | ALDH1A1 (0.36) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440643-B2 | Inhibitors of beta-lactamase | METHYLGENE INC. (CA) | 2013-05-14 | — | — | US | claimed |
| US-8440643-B2 | Inhibitors of beta-lactamase | METHYLGENE INC. (CA) | 2013-05-14 | — | — | US | disclosed |
| US-20100317625-A1 | NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE | 92229129 QUEBEC INC. (CA) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317625-A1 | NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE | MGAM, BPGM, PPME1 | TRPV4 4778/4885SLC22A12 2766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.