SCHEMBL3480994

SCHEMBL3480994

CC(C)(C)OC(=O)C(C(=O)OC(C)(C)C)C(C)(C)O[C]=O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
KMT2A Q03164 1/20 0.34
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL766244 0.82 LMNA (0.33) LMNAKMT2A
SCHEMBL8006822 0.78 GSR (0.37)
SCHEMBL4956405 0.70 DGAT1 (0.36) LMNAKMT2ADGAT1
SCHEMBL271041 0.69
SCHEMBL3883972 0.68 CA12 (0.33) LMNAKMT2ADGAT1
SCHEMBL635059 0.67 KMT2A (0.40) LMNAKMT2ADGAT1
SCHEMBL9318330 0.67 LMNA (0.33) LMNAKMT2ADGAT1
SCHEMBL30476258 0.67 LMNA (0.33) LMNAKMT2ADGAT1
SCHEMBL635058 0.67 KMT2A (0.40) LMNAKMT2ADGAT1
SCHEMBL10526055 0.67 CA1 (0.37) LMNAKMT2ADGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100159446-A1 Detection Assays and Use Thereof ENSEMBLE THERAPEUTICS CORPORATION 2010-06-24 US disclosed