SCHEMBL766244

SCHEMBL766244

CC(C(=O)OC(C)(C)C)C(C)(C)O[C]=O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
KMT2A Q03164 1/20 0.33
CA12 O43570 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3480994 0.82 LMNA (0.34) LMNAKMT2A
SCHEMBL11629491 0.80 TSHR (0.34)
SCHEMBL5872628 0.74 CA12 (0.35) LMNAKMT2ACA12CA1CA2
SCHEMBL12027691 0.73 CA1 (0.39) LMNAKMT2ACA12CA14CA1
SCHEMBL271041 0.73
SCHEMBL3883972 0.71 CA12 (0.33) LMNAKMT2ACA12CA14CA1
SCHEMBL107710 0.70 CA12 (0.34) LMNAKMT2ACA12CA14CA1
SCHEMBL10526055 0.70 CA1 (0.37) LMNAKMT2ACA12CA14CA1
SCHEMBL11800116 0.69 DGAT1 (0.39) CA1CA2CA7
SCHEMBL28488080 0.68 CTSS (0.36) LMNAKMT2ACA12CA14CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200072823-A1 Enzyme-Amplified Redox Micoarray Detection Process CUSTOMARRAY, INC. (US) 2020-03-05 US disclosed
US-10286377-B1 Electrode array device having an adsorbed porous reaction layer CUSTOMARRAY, INC. (US) 2019-05-14 US disclosed
US-10035147-B2 Wafer with gel-based biochips for electrochemical synthesis and electrical detection of polymers INTEL CORPORATION (US) 2018-07-31 US disclosed
US-9458199-B2 Antigen surrogates in autoimmune disease OPKO PHARMACEUTICALS, LLC (US) 2016-10-04 US disclosed
US-20150231633-A1 GEL-BASED BIO CHIP FOR ELECTROCHEMICAL SYNTHESIS AND ELECTRICAL DETECTION OF POLYMERS INTEL CORP (US) 2015-08-20 US disclosed
US-20150212032-A1 METHOD AND APPARATUS FOR MATCH QUALITY ANALYSIS OF ANALYTE BINDING INTEL CORPORATION 2015-07-30 US disclosed
US-9085461-B2 Method and apparatus to fabricate polymer arrays on patterned wafers using electrochemical synthesis INTEL CORPORATION (US) 2015-07-21 US disclosed
US-8999724-B2 Method and apparatus for match quality analysis of analyte binding INTEL CORPORATION (US) 2015-04-07 US disclosed
US-8940143-B2 Gel-based bio chip for electrochemical synthesis and electrical detection of polymers INTEL CORPORATION (US) 2015-01-27 US disclosed
US-8759259-B2 Compositions and methods for producing cyclic peptoid libraries THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-06-24 US disclosed
EP-1952155-A2 METHOD AND CMOS-BASED DEVICE TO ANALYZE MOLECULES AND NANOMATERIALS BASED ON THE ELECTRICAL READOUT OF SPECIFIC BINDING EVENTS ON FUNCTIONALIZED ELECTRODES Intel Corporation (INTEL) (US) 2008-08-06 EP disclosed
US-20080157786-A1 Quality control methods for the manufacture of polymer arrays INTEL CORPORATION 2008-07-03 US disclosed
US-20080160635-A1 Method and apparatus for combined electrochemical synthesis and detection of analytes INTEL CORPORATION (US) 2008-07-03 US disclosed
WO-2008048222-A2 METHOD AND CMOS-BASED DEVICE TO ANALYZE MOLECULES AND NANOMATERIALS BASED ON THE ELECTRICAL READOUT OF SPECIFIC BINDING EVENTS ON FUNCTIONALIZED ELECTRODES INTEL CORPORATION (US) 2008-04-24 WO disclosed
US-20070048746-A1 Beam emitter, microfluidic channel, spectrometer and detector; binding between reporter molecules and analyte; microelectric mechanical system INTEL CORPORATION (US) 2007-03-01 US disclosed
WO-2006133042-A2 METHOD AND APPARATUS TO FABRICATE POLYMER ARRAYS ON PATTERNED WAFERS USING ELECTROCHEMICAL SYNTHESIS INTEL CORPORATION (US) 2006-12-14 WO disclosed
US-20060275927-A1 Method and apparatus to fabricate polymer arrays on patterned wafers using electrochemical synthesis INTEL CORPORATION (US) 2006-12-07 US disclosed
US-6093302-A Electrochemical solid phase synthesis COMBIMATRIX CORPORATION (US) 2000-07-25 US disclosed
EP-0617622-A1 USE OF RENIN INHIBITORS FOR THE TREATMENT OF GLAUCOMA FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-10-05 EP disclosed
WO-1993012796-A1 USE OF RENIN INHIBITORS FOR THE TREATMENT OF GLAUCOMA FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-07-08 WO disclosed