SCHEMBL3481659

SCHEMBL3481659

O=C(c1ccc[nH]1)c1cc(Cl)ccc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.59
L3MBTL1 Q9Y468 3/20 0.59
CYP1A2 P05177 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
KDM4E B2RXH2 1/20 0.59
KMT2A Q03164 4/20 0.51
LMNA P02545 3/20 0.51
ALDH1A1 P00352 5/20 0.50
NPC1 O15118 4/20 0.50
RAB9A P51151 3/20 0.50
TP53 P04637 1/20 0.50
KCNMA1 Q12791 1/20 0.49
MEN1 O00255 3/20 0.46
HSD17B10 Q99714 3/20 0.46
ATM Q13315 1/20 0.46
GAA P10253 2/20 0.46
CYP1A1 P04798 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP1B1 Q16678 2/20 0.46
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9653610 0.87 MAPT (0.56) MAPTL3MBTL1CYP1A2SMN1; SMN2KDM4E
SCHEMBL9686196 0.85 MAPT (0.61) MAPTL3MBTL1CYP1A2SMN1; SMN2KDM4E
SCHEMBL9772541 0.81 KMT2A (0.54) MAPTL3MBTL1CYP1A2SMN1; SMN2KDM4E
SCHEMBL18393224 0.81 MAPT (0.50) MAPTL3MBTL1CYP1A2SMN1; SMN2KDM4E
SCHEMBL5532280 0.79 CYP1A2 (0.62) MAPTCYP1A2SMN1; SMN2KDM4EKMT2A
SCHEMBL8160214 0.78 ALDH1A1 (0.71) MAPTCYP1A2SMN1; SMN2KDM4ELMNA
SCHEMBL6424225 0.77 SMN1; SMN2 (0.67) MAPTL3MBTL1CYP1A2SMN1; SMN2KDM4E
SCHEMBL18393121 0.76 MAPT (0.46) MAPTL3MBTL1CYP1A2SMN1; SMN2KDM4E
SCHEMBL29612638 0.75 ALDH1A1 (0.63) MAPTSMN1; SMN2KMT2ALMNAALDH1A1
SCHEMBL230930 0.75 ALDH1A1 (0.63) MAPTSMN1; SMN2KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8729219-B2 Polyarylene block copolymer having sulfonic acid group and use thereof JSR CORPORATION (JP) 2014-05-20 US disclosed
US-20130085236-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF JSR CORPORATION (JP) 2013-04-04 US disclosed
US-8273499-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2012-09-25 US disclosed
US-8273499-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2012-09-25 US disclosed
US-8273499-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2012-09-25 US disclosed
US-20120052412-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF HONDA MOTOR CO., LTD. (JP) 2012-03-01 US disclosed
US-20100062311-A1 MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL HONDA MOTOR CO., LTD. (JP) 2010-03-11 US disclosed
US-20100062311-A1 MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL HONDA MOTOR CO., LTD. (JP) 2010-03-11 US disclosed
US-20100062311-A1 MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL HONDA MOTOR CO., LTD. (JP) 2010-03-11 US disclosed