Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 18/20 | 0.55 |
| ▸ | CNR2 | P34972 | 11/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482043 | 0.75 | CNR1 (0.67) | CNR1CNR2ADORA2AADORA1 | |
| SCHEMBL5355501 | 0.75 | CNR1 (0.70) | CNR1CNR2 | |
| SCHEMBL197002 | 0.72 | BCAT2 (0.71) | — | |
| SCHEMBL5246914 | 0.72 | CNR1 (0.77) | CNR1CNR2 | |
| SCHEMBL5359532 | 0.71 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL3481940 | 0.71 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL28270443 | 0.71 | BCAT2 (0.69) | — | |
| SCHEMBL13070816 | 0.70 | CNR1 (0.80) | CNR1CNR2 | |
| SCHEMBL6590788 | 0.68 | IKBKB (0.52) | — | |
| SCHEMBL11012074 | 0.68 | MAP4K4 (0.49) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100063032-A1 | SUBSTITUTED PYRIDO[2,3-D]PYRIMIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063032-A1 | SUBSTITUTED PYRIDO[2,3-D]PYRIMIDINE DERIVATIVES AS CANNABINOID-1 RECEPTOR MODULATORS | CNR1, CNR2, FAAH | CNR1 1/4885CNR2 2/4885ADORA2A 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.