SCHEMBL3482035

SCHEMBL3482035

C[SiH](O)CCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.48
ALDH1A1 P00352 2/20 0.45
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CASP1 P29466 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TAAR1 Q96RJ0 3/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
ATM Q13315 1/20 0.43
KEAP1 Q14145 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
CYP2A6 P11509 1/20 0.42
HTR2A P28223 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.42
NOS1 P29475 1/20 0.42
TP53 P04637 1/20 0.40
AOC3 Q16853 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17236295 0.83 SIGMAR1 (0.50) ALOX15HDAC1HDAC2
SCHEMBL4514776 0.80 TDP1 (0.52) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL476138 0.80 TP53 (0.50) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL7749434 0.80 ALDH1A1 (0.48) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL8577999 0.77 TDP1 (0.44) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL3481488 0.76 ALDH1A1 (0.44) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL4327818 0.76 TDP1 (0.48) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL9422114 0.76 ALDH1A1 (0.45) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL8382117 0.76 ALDH1A1 (0.44) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL8380723 0.76 MAOB (0.44) TDP1ALDH1A1HPGDALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160207782-A1 POLYSILOCARB BASED SILICON CARBIDE MATERIALS, APPLICATIONS AND DEVICES MELIOR INNOVATIONS, INC. (US) 2016-07-21 US disclosed
US-20160207783-A1 HIGH PURITY POLYSILOCARB DERIVED SILICON CARBIDE MATERIALS, APPLICATIONS AND PROCESSES MELIOR INNOVATIONS, INC. (US) 2016-07-21 US disclosed
US-20160207781-A1 HIGH PURITY POLYSILOCARB MATERIALS, APPLICATIONS AND PROCESSES MELIOR INNOVATIONS, INC. (US) 2016-07-21 US disclosed
US-20160207836-A1 PRESSED AND SELF SINTERED POLYMER DERIVED SiC MATERIALS, APPLICATIONS AND DEVICES MELIOR INNOVATIONS, INC. (US) 2016-07-21 US disclosed
US-20160207780-A1 METHODS OF PROVIDING HIGH PURITY SiOC AND SiC MATERIALS MELIOR INNOVATIONS, INC. (US) 2016-07-21 US disclosed
EP-2128897-B1 SILICON DIELECTRIC TREATING AGENT FOR USE AFTER ETCHING, PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJITSU LTD (JP) 2015-05-06 EP disclosed
US-8716209-B2 Agent for post-etch treatment of silicon dielectric film, method of manufacturing semiconductor device, and semiconductor device FUJITSU LIMITED (JP) 2014-05-06 US disclosed
US-20100007031-A1 AGENT FOR POST-ETCH TREATMENT OF SILICON DIELECTRIC FILM, METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2010-01-14 US disclosed
EP-2128897-A1 SILICON DIELECTRIC TREATING AGENT FOR USE AFTER ETCHING, PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE Fujitsu Limited (JP) 2009-12-02 EP disclosed
US-7388059-B2 Ethylene polymer, catalyst for producing thereof and method for producing thereof JAPAN POLYETHYLENE CORPORATION (JP) 2008-06-17 US disclosed
EP-0318193-A2 Methods of making implantable, inflatable silicone reservoirs DOW CORNING WRIGHT CORPORATION (US) 1989-05-31 EP disclosed
US-4497919-A WAXES, FILMS, EMULSIFIERS TURTLE WAX, INC. (US) 1985-02-05 US disclosed
US-4380591-A POLYESTER URETHANE COPOLYMER UNION CARBIDE CORPORATION (US) 1983-04-19 US disclosed
US-4379757-A Tertiary amine catalyst mixtures useful in cellular polyurethane formation UNION CARBIDE CORPORATION (US) 1983-04-12 US disclosed
EP-0048985-A1 Process for cellular polyurethane formation using tertiary amine catalyst mixtures UNION CARBIDE CORPORATION (US) 1982-04-07 EP disclosed
US-4145505-A BIS(O-CHLOROBENZOYL)PEROXIDE AS CROSSLINKER AKZONA INCORPORATED (US) 1979-03-20 US disclosed
US-4070313-A PHENOLIC RESOLE, BLOWING AGENT, POLYSILOXANE UNION CARBIDE CORPORATION (US) 1978-01-24 US disclosed
US-4038210-A BETA-AMINO NITRILE CATALYSTS FOR POLYURETHANE PREPARATION UNION CARBIDE CORPORATION (US) 1977-07-26 US disclosed
US-4012445-A Beta-amino carbonyl catalysts for polyurethane preparation UNION CARBIDE CORPORATION (US) 1977-03-15 US disclosed
US-3954749-A MORPHOLINE DERIVATIVES OF AMIDES UNION CARBIDE CORPORATION (US) 1976-05-04 US disclosed