SCHEMBL7749434

SCHEMBL7749434

C[SiH](CCc1ccccc1)[SiH](C)CCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
CASP1 P29466 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TAAR1 Q96RJ0 3/20 0.46
ATM Q13315 1/20 0.46
TDP1 Q9NUW8 2/20 0.46
CYP2A6 P11509 1/20 0.46
HTR2A P28223 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
TP53 P04637 1/20 0.43
AOC3 Q16853 1/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
KCNH2 Q12809 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476138 0.84 TP53 (0.50) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL8380723 0.80 MAOB (0.44) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL9422114 0.80 ALDH1A1 (0.45) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL8382117 0.80 ALDH1A1 (0.44) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL3481488 0.80 ALDH1A1 (0.44) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL3482035 0.80 TDP1 (0.48) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL2457739 0.78 ALDH1A1 (0.52) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL8384474 0.77 CYP1A2 (0.52) ALDH1A1ALOX15TAAR1TDP1CYP2A6
SCHEMBL8381080 0.77 ALDH1A1 (0.41) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL837631 0.77 ALDH1A1 (0.41) ALDH1A1HPGDALOX15ALOX12CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0697630-B1 X-ray mask support CANON KK (JP) 2001-01-03 EP disclosed
EP-0630933-B1 A method of producing a semiconducting material NIPPON OIL CO LTD (JP) 1999-04-14 EP disclosed
US-5700400-A Method for producing a semiconducting material NIPPON OIL CO., LTD. (JP) 1997-12-23 US disclosed
EP-0551771-B1 Process for producing polysilanes NIPPON OIL CO LTD (JP) 1997-07-30 EP disclosed
US-5620531-A Photovoltaic element NIPPON OIL CO., LTD. (JP) 1997-04-15 US disclosed
EP-0310124-B1 Process for producing an X-ray mask CANON KK (JP) 1997-03-19 EP disclosed
EP-0717451-A2 Photovoltaic element NIPPON OIL CO., LTD. (JP) 1996-06-19 EP disclosed
EP-0697630-A1 X-ray mask support CANON KABUSHIKI KAISHA (JP) 1996-02-21 EP disclosed
EP-0630933-A2 A method of producing a semiconducting material NIPPON OIL CO. LTD. (JP) 1994-12-28 EP disclosed
US-5304622-A Process for producing polysilanes NIPPON OIL COMPANY, LTD. (JP) 1994-04-19 US disclosed
EP-0551771-A2 Process for producing polysilanes NIPPON OIL CO. LTD. (JP) 1993-07-21 EP disclosed
US-5101420-A X-RAY MASK SUPPORT AND PROCESS FOR PREPARATION THEREOF CANON KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed
EP-0310124-A2 Process for producing an X-ray mask CANON KABUSHIKI KAISHA (JP) 1989-04-05 EP disclosed