Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CPN1 | P15169 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL927270 | 0.96 | CYP3A4 (0.44) | CYP3A4CASP1RECQLCPN1CPB2 | |
| SCHEMBL272384 | 0.95 | CYP3A4 (0.52) | CYP3A4CASP1RECQLCPN1CPB2 | |
| SCHEMBL17073473 | 0.94 | CYP3A4 (0.42) | CYP3A4CASP1RECQLCPN1CPB2 | |
| SCHEMBL15171130 | 0.93 | MAOA (0.46) | CYP3A4CASP1RECQLCPN1CPB2 | |
| SCHEMBL17073489 | 0.92 | CYP3A4 (0.41) | CYP3A4CASP1RECQLCPN1CPB2 | |
| SCHEMBL9755239 | 0.90 | ESR1 (0.59) | CYP3A4CASP1RECQLCPN1CPB2 | |
| SCHEMBL7002896 | 0.87 | ALDH1A1 (0.53) | CYP3A4CA1CA2ALDH1A1CYP2D6 | |
| SCHEMBL5893842 | 0.86 | MAPKAPK2 (0.49) | CYP3A4CASP1RECQLCPN1CPB2 | |
| SCHEMBL25128183 | 0.85 | ACHE (0.48) | CYP3A4CASP1RECQLCPN1CPB2 | |
| SCHEMBL25128159 | 0.85 | ACHE (0.48) | CYP3A4CASP1RECQLCPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420764-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20120178894-A1 | COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER | INAGAKI JYUN-ICHI (JP) | 2012-07-12 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| US-7507450-B2 | Varnish for forming liquid crystal alignment layer and liquid crystal display element using the same | CHISSO CORPORATION (JP) | 2009-03-24 | — | — | US | disclosed |
| US-7373060-B2 | Optical waveguide using polymer composed of silsesquioxane derivative | CHISSO CORPORATION (JP) | 2008-05-13 | — | — | US | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20060204192-A1 | Optical waveguide using polymer composed of silsesquioxane derivative | JNC CORPORATION (JP) | 2006-09-14 | — | — | US | disclosed |
| US-20060204680-A1 | Varnish for forming liquid crystal alignment layer and liquid crystal display element using the same | JNC CORPORATION (JP) | 2006-09-14 | — | — | US | disclosed |
| US-6949281-B1 | Varnish composition and liquid-crystal display element | CHISSO CORPORATION (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | CHISSO CORPORATION (JP) | 2005-01-13 | — | — | US | disclosed |
| US-6746730-B1 | VARNISH COMPOSITION WHICH COMPRISES POLYMER COMPONENT CONTAINING TWO DIFFERENT POLYAMIC ACIDS, SOLUBLE POLYIMIDE, AND SOLVENT FOR DISSOLVING POLYMER COMPONENT | CHISSO CORPORATION (JP) | 2004-06-08 | — | — | US | disclosed |
| US-6685997-B1 | SOLUTION CONTAINING POLYAMIC ACIDS, POLYAMIDES AND POLYIMIDES; ALIGNMENT FILM; WELL BALANCED ELECTRICAL CHARACTERISTICS; ELIMINATES IMAGE STICKING | CHISSO CORPORATION (JP) | 2004-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | C1S, H1-4, H1-0 | CYP3A4 1082/4885CASP1 439/4885RECQL 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.