SCHEMBL3482930

SCHEMBL3482930

Cc1cc(C)cc([SiH2]Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
TSHR P16473 2/20 0.40
ACHE P22303 2/20 0.33
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
TPMT P51580 1/20 0.32
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
C1S P09871 1/20 0.31
PRSS3 P35030 1/20 0.31
SELL P14151 1/20 0.30
SELP P16109 1/20 0.30
SELE P16581 1/20 0.30
HMBS P08397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31598847 0.73
SCHEMBL28534132 0.71 ALDH1A1 (0.42) ALDH1A1TSHRACHETPMTPRSS1
SCHEMBL26115 0.71
SCHEMBL341533 0.71 ALDH1A1 (0.67) ALDH1A1TSHRACHETPMTPRSS1
SCHEMBL27450096 0.69 ALDH1A1 (0.47) ALDH1A1TSHRACHETPMTPRSS1
SCHEMBL3481606 0.69 ALDH1A1 (0.45) ALDH1A1TSHRACHEPGK1PGK2
SCHEMBL277212 0.69
SCHEMBL12814450 0.68
SCHEMBL24625912 0.67 ALDH1A1 (0.38) ALDH1A1TSHRACHETPMT
SCHEMBL3481737 0.67 RAPGEF4 (0.39) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110358090-A A kind of method of support type phosphazene catalyst catalyzed preparation of poly siloxanes 青岛科技大学 2019-10-22 CN claimed
CN-106467563-B The synthetic method and its midbody compound of chondroitin sulfate tetrose 北京大学 2019-08-06 CN claimed
CN-110003265-A A kind of preparation method of 1,4- butine two (trialkyl silyl) ester 珠海市赛纬电子材料股份有限公司 2019-07-12 CN claimed
CN-107523809-B A kind of preparation method of Silicone hard nano protecting coating 江苏菲沃泰纳米科技有限公司 2019-06-25 CN claimed
CN-109897181-A A kind of preparation method of high molecular weight MQ silicone resin 江西蓝星星火有机硅有限公司 2019-06-18 CN claimed
CN-107523808-B A kind of preparation method of organic silicon nano protective coating 江苏菲沃泰纳米科技有限公司 2019-05-10 CN claimed
CN-109439290-A A kind of environmental protection organic heat carrier and preparation method thereof 山东恒利热载体工程技术有限公司 2019-03-08 CN claimed
CN-109317219-A A kind of method of modifying of silicon oxide material 嘉兴柴薪科技有限公司 2019-02-12 CN claimed
CN-109320720-A A kind of anhydrous synthesis preparation method of MQ type organic siliconresin 深圳市广业电子科技有限公司 2019-02-12 CN claimed
CN-109280170-A A kind of functional polysiloxanes copolymer preparation method of phosphonitrile catalysis 青岛科技大学 2019-01-29 CN claimed
CN-101307039-A Method for producing epoxide CHINA PETROCHEMICAL CORP (CN) 2008-11-19 CN claimed
CN-101279960-A Preparation of epoxide CHINA PETROCHEMICAL CORP (CN) 2008-10-08 CN claimed
CN-101239726-A Organic silicon micro-pore zeolite and its synthetic method and application CHINA PETROLEUM & CHEMICAL (CN) 2008-08-13 CN claimed
CN-101239728-A Micro-pore zeolite, preparation method and application thereof CHINA PETROLEUM & CHEMICAL (CN) 2008-08-13 CN claimed
CN-100406443-C Process for preparing quinolone antibiotic intermediates PROCTER & GAMBLE (US) 2008-07-30 CN claimed
CN-101172254-A Organosilicon micropore zeolite, synthesizing method and uses thereof CHINA PETROLEUM CHEM CO LTD (CN) 2008-05-07 CN claimed
CN-101121523-A Organic silicon micro-pore zeolite and synthesizing method thereof CHINA PETROLEUM & CHEMICAL (CN) 2008-02-13 CN claimed
CN-101121524-A Organic silicon micro-pore zeolite, synthesizing method and its application CHINA PETROLEUM & CHEMICAL (CN) 2008-02-13 CN claimed
CN-1232508-C Cyclization process steps for making quinolones and naphthyridines P & G CO (US) 2005-12-21 CN claimed
CN-1668599-A Process for preparing quinolone antibiotic intermediates PROCTER & GAMBLE (US) 2005-09-14 CN claimed