Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SOD1 | P00441 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482900 | 0.90 | KMT2A (0.52) | KMT2AMEN1MAPTCCR3LMNA | |
| SCHEMBL3483019 | 0.88 | MAPT (0.53) | KMT2AMEN1MAPTLMNAADRB1 | |
| SCHEMBL3482899 | 0.87 | CCR3 (0.57) | KMT2AMAPTCCR3ADRB1HTR2A | |
| SCHEMBL3482768 | 0.86 | GFER (0.48) | KMT2AMEN1MAPTCCR3LMNA | |
| SCHEMBL3482303 | 0.84 | HSD17B10 (0.51) | KMT2AMAPTCCR3LMNAADRB1 | |
| SCHEMBL3482506 | 0.84 | LMNA (0.49) | KMT2AMEN1MAPTCCR3LMNA | |
| SCHEMBL3482588 | 0.82 | ADRB1 (0.49) | KMT2AMEN1MAPTCCR3LMNA | |
| SCHEMBL3482665 | 0.82 | LMNA (0.50) | KMT2AMEN1MAPTLMNAADRB1 | |
| SCHEMBL3483021 | 0.81 | MC4R (0.46) | KMT2AMEN1MAPTCCR3LMNA | |
| SCHEMBL3482657 | 0.80 | ADRB1 (0.48) | KMT2AMEN1MAPTCCR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150550-A1 | NOVEL CARBAMOYLOXY ARYL ALKAN ARYLPIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND AND METHOD FOR TREATING PAIN, ANXIETY AND DEPRESSION BY ADMINISTERING THE COMPOUND | SK Holdings Co., Ltd. (KR) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008140197-A1 | NOVEL CARBAMOYLOXY ARYL ALKAN ARYLPIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND AND METHOD FOR TREATING PAIN, ANXIETY AND DEPRESSION BY ADMINISTERING THE COMPOUND | SK HOLDINGS CO., LTD. (KR) | 2008-11-20 | — | — | WO | disclosed |