Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482588 | 0.89 | ADRB1 (0.49) | MAPTUSP2LMNAADRB1HTR2A | |
| SCHEMBL3482937 | 0.88 | KMT2A (0.50) | MAPTLMNAADRB1HTR2AHTR2B | |
| SCHEMBL3482768 | 0.84 | GFER (0.48) | MAPTLMNAADRB1HTR2AHTR2B | |
| SCHEMBL3482303 | 0.83 | HSD17B10 (0.51) | MAPTUSP2LMNAADRB1HTR2A | |
| SCHEMBL3482506 | 0.82 | LMNA (0.49) | MAPTLMNAADRB1HTR2AHTR2B | |
| SCHEMBL3482900 | 0.82 | KMT2A (0.52) | MAPTLMNAADRB1HTR2AHTR2B | |
| SCHEMBL3482899 | 0.80 | CCR3 (0.57) | MAPTADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL3482657 | 0.78 | ADRB1 (0.48) | MAPTLMNAADRB1HTR2AHTR2B | |
| SCHEMBL2114511 | 0.78 | ADRB1 (0.78) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL3482672 | 0.76 | MAPT (0.50) | MAPTLMNAADRB1HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150550-A1 | NOVEL CARBAMOYLOXY ARYL ALKAN ARYLPIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND AND METHOD FOR TREATING PAIN, ANXIETY AND DEPRESSION BY ADMINISTERING THE COMPOUND | SK Holdings Co., Ltd. (KR) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008140197-A1 | NOVEL CARBAMOYLOXY ARYL ALKAN ARYLPIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND AND METHOD FOR TREATING PAIN, ANXIETY AND DEPRESSION BY ADMINISTERING THE COMPOUND | SK HOLDINGS CO., LTD. (KR) | 2008-11-20 | — | — | WO | disclosed |