SCHEMBL3483215

SCHEMBL3483215

CC(C)=CCc1c(O)c(CC2=C(O)C(C)(C)C(O)=C(C(=O)C(C)C)C2=O)c(O)c(C(=O)C(C)C)c1O

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PTGES O14684 4/20 0.37
▸ ALOX5 P09917 5/20 0.36
▸ FASN P49327 1/20 0.36
▸ HIF1A Q16665 7/20 0.35
▸ EPAS1 Q99814 7/20 0.35
▸ PTGS1 P23219 1/20 0.34
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ SOAT2 O75908 1/20 0.32
▸ SOAT1 P35610 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ AKR1B10 O60218 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29928966 0.86 FASN (0.48) PTGESALOX5FASNHIF1AEPAS1
SCHEMBL23044598 0.79 PTGES (0.35) PTGESALOX5FASNHIF1AEPAS1
SCHEMBL29929660 0.79 PTGES (0.33) PTGESALOX5FASNPTGS1
SCHEMBL29929432 0.79 PTGES (0.33) PTGESALOX5FASNPTGS1
SCHEMBL29377594 0.78 FASN (0.46) PTGESALOX5FASNPTGS1
SCHEMBL24075655 0.78 MEN1 (0.49) PTGESALOX5HIF1AEPAS1PTGS1
SCHEMBL23044596 0.77 ALOX5 (0.35) PTGESALOX5HIF1AEPAS1MEN1
SCHEMBL31580515 0.75 MEN1 (0.49) PTGESALOX5HIF1AEPAS1PTGS1
SCHEMBL3483228 0.73 PTGES (0.41) PTGESALOX5FASNHIF1AMEN1
SCHEMBL24074936 0.69 PTGES (0.60) PTGESALOX5PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 — — US claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 — — WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 — — WO claimed
US-7854946-B1 Anti-inflammatory and anti-HIV compositions and methods of use IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2010-12-21 — — US claimed
WO-2010092162-A1 NEUROACTIVE PLANT EXTRACT FROM HYPERICUM POLYANTHEMUM UNIVERSITE DE ROUEN (FR) 2010-08-19 — — WO claimed
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES NATURAL EXTRACTION SYS LLC (US) 2026-02-19 — — US disclosed
US-12409152-B2 Compositions and methods related to dissolved oxides Natural Extraction Systems, LLC (US) 2025-09-09 — — US disclosed
US-20250161394-A1 Compositions Comprising Kavalactones NATURAL EXTRACTION SYS LLC (US) 2025-05-22 — — US disclosed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US disclosed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 — — US disclosed
US-20220362169-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES Natural Extraction Systems, LLC 2022-11-17 — — US disclosed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 — — WO disclosed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 — — WO disclosed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 — — WO disclosed
WO-2021042001-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES Natural Extraction Systems, LLC (US) 2021-03-04 — — WO disclosed
US-7854946-B1 Anti-inflammatory and anti-HIV compositions and methods of use IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2010-12-21 — — US disclosed
WO-2010092162-A1 NEUROACTIVE PLANT EXTRACT FROM HYPERICUM POLYANTHEMUM UNIVERSITE DE ROUEN (FR) 2010-08-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB PTGES 1679/4885ALOX5 264/4885FASN 1020/4885
US-12409152-B2 Compositions and methods related to dissolved oxides PRKG2, PRKG1, CIT PTGES 1236/4885ALOX5 260/4885FASN 1957/4885
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES SCO2, CNR2, CNR1 PTGES 338/4885ALOX5 307/4885FASN 1507/4885
US-20220362169-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES PRKG2, PRKG1, CIT PTGES 1236/4885ALOX5 260/4885FASN 1957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback