Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.67 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | VDR | P11473 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17279794 | 0.81 | NR1H2 (0.86) | NR1H2NR1H3ADORA2AADORA1DYRK1A | |
| SCHEMBL3975246 | 0.81 | NR1H2 (0.67) | NR1H2NR1H3ADORA2AADORA1DYRK1A | |
| SCHEMBL2485799 | 0.80 | XDH (0.49) | NR1H2NR1H3DYRK1ACLK4NOTUM | |
| SCHEMBL11401007 | 0.79 | CYP1A2 (0.59) | NR1H2NR1H3NOTUMCYP1A2CYP2C9 | |
| SCHEMBL30149870 | 0.77 | NR1H2 (0.89) | NR1H2NR1H3ADORA2AADORA1DCUN1D1 | |
| SCHEMBL29035880 | 0.77 | NR1H2 (0.89) | NR1H2NR1H3ADORA2AADORA1DCUN1D1 | |
| SCHEMBL17279741 | 0.77 | NR1H2 (0.72) | NR1H2NR1H3ADORA2AADORA1DYRK1A | |
| SCHEMBL15117074 | 0.76 | NR1H2 (0.80) | NR1H2NR1H3ADORA2AADORA1DYRK1A | |
| SCHEMBL10476791 | 0.75 | NR1H2 (0.73) | NR1H2NR1H3ADORA2AADORA1DYRK1A | |
| SCHEMBL10476798 | 0.75 | NR1H2 (0.69) | NR1H2NR1H3ADORA2AADORA1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004159-A1 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES | GENFIT (FR) | 2010-01-07 | — | — | US | disclosed |
| CN-101522192-A | Substituted imidazolone derivatives, preparation and uses | GENFIT (FR) | 2009-09-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004159-A1 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES | IPO5, PPIP5K2, IPO4 | NR1H2 2848/4885NR1H3 2297/4885ADORA2A 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.