Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4446684 | 0.86 | LMNA (0.47) | CHRNA7SMN1; SMN2LMNASLC6A4SLC6A2 | |
| SCHEMBL1191221 | 0.84 | SLC6A4 (0.63) | CHRNA7SMN1; SMN2CYP2C9CYP2C19HPGD | |
| SCHEMBL11011298 | 0.81 | SLC6A2 (0.44) | CHRNA7SMN1; SMN2CYP2C9CYP2C19HPGD | |
| SCHEMBL5659551 | 0.79 | SMN1; SMN2 (0.41) | CHRNA7SMN1; SMN2CYP2C9CYP2C19HPGD | |
| SCHEMBL9472324 | 0.78 | APOBEC3G (0.61) | CHRNA7SMN1; SMN2CYP2C9CYP2C19HPGD | |
| SCHEMBL5333062 | 0.78 | CHRNA7 (0.53) | CHRNA7SMN1; SMN2CYP2C9CYP2C19HPGD | |
| SCHEMBL223717 | 0.78 | CHRNA7 (0.53) | CHRNA7SMN1; SMN2CYP2C9CYP2C19HPGD | |
| SCHEMBL29582043 | 0.78 | CHRNA7 (0.53) | CHRNA7SMN1; SMN2CYP2C9CYP2C19HPGD | |
| SCHEMBL1786728 | 0.78 | CHRNA7 (0.53) | CHRNA7SMN1; SMN2CYP2C9CYP2C19HPGD | |
| SCHEMBL15850627 | 0.77 | CHRNA7 (0.51) | CHRNA7SMN1; SMN2CYP2C9CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004159-A1 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES | GENFIT (FR) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004159-A1 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES | IPO5, PPIP5K2, IPO4 | CHRNA7 3392/4885SMN1; SMN2 627/4885CYP2C9 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.