Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CRHBP | P24387 | 2/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 7/20 | 0.47 |
| ▸ | RXRB | P28702 | 6/20 | 0.47 |
| ▸ | RXRG | P48443 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3485013 | 1.00 | PTGER1 (0.54) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL8243864 | 0.95 | PTGER1 (0.49) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL13498116 | 0.91 | RXRA (0.51) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL3485351 | 0.90 | PTGER1 (0.49) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL3485347 | 0.90 | PTGER1 (0.49) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL13498117 | 0.90 | RXRA (0.50) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL3484771 | 0.90 | RXRA (0.50) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL3484769 | 0.90 | RXRA (0.50) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL3484264 | 0.89 | PTGER1 (0.48) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL3484259 | 0.89 | PTGER1 (0.48) | PTGER1PTGER4PTGER3PTGER2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609727-B2 | Dicarboxylic acid derivatives and their use | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-12-17 | — | — | US | disclosed |
| US-20100029772-A1 | Dicarboxylic Acid Derivatives and their Use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029772-A1 | Dicarboxylic Acid Derivatives and their Use | PC, SLC25A1, GOT2 | PTGER1 2299/4885PTGER4 2636/4885PTGER3 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.