Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.92 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13254544 | 1.00 | MAPT (0.92) | MAPTCA1CYP1A2RECQLSLC6A3 | |
| SCHEMBL14292322 | 1.00 | MAPT (0.92) | MAPTCA1CYP1A2RECQLSLC6A3 | |
| SCHEMBL30031079 | 1.00 | MAPT (0.92) | MAPTCA1CYP1A2RECQLSLC6A3 | |
| SCHEMBL28413868 | 0.96 | MAPT (1.00) | MAPTCA1CYP1A2RECQLSLC6A3 | |
| SCHEMBL7055028 | 0.82 | MAPT (0.61) | MAPTCA1LMNAKDM4EHPGD | |
| SCHEMBL14292320 | 0.82 | MAPT (0.61) | MAPTCA1LMNAKDM4EHPGD | |
| SCHEMBL3487513 | 0.82 | MAPT (0.61) | MAPTCA1LMNAKDM4EHPGD | |
| SCHEMBL7053572 | 0.82 | MAPT (0.61) | MAPTCA1LMNAKDM4EHPGD | |
| SCHEMBL4754009 | 0.82 | MAPT (0.61) | MAPTCA1LMNAKDM4EHPGD | |
| SCHEMBL4754008 | 0.82 | MAPT (0.61) | MAPTCA1LMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111235187-B | Method for preparing beta-hydroxyketone by reacting enzyme-catalyzed cyclic ketone with aromatic aldehyde | 岭南师范学院 | 2022-12-06 | — | — | CN | disclosed |
| CN-111235187-A | Method for preparing β -hydroxyketone by reacting cyclic ketone with aromatic aldehyde under enzyme catalysis | 岭南师范学院 | 2020-06-05 | — | — | CN | disclosed |
| US-8399684-B2 | Sulfonamide-based organocatalysts and method for their use | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2013-03-19 | — | — | US | disclosed |
| US-20100184986-A1 | SULFONAMIDE-BASED ORGANOCATALYSTS AND METHOD FOR THEIR USE | The State of Oregon acting by and through the State Board of Higher Education on behalf of Orego | 2010-07-22 | — | — | US | disclosed |
| WO-2009039181-A2 | SULFONAMIDE-BASED ORGANOCATALYSTS AND METHOD FOR THEIR USE | STATE OF OREGON ACTING BY & THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OR. STATE UNIV. (US) | 2009-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184986-A1 | SULFONAMIDE-BASED ORGANOCATALYSTS AND METHOD FOR THEIR USE | ALDH7A1, SULT1A1, SULT2A1 | MAPT 3451/4885CA1 1253/4885CYP1A2 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.