⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662033 | 1.00 | — | — | |
| SCHEMBL11391091 | 0.85 | USP2 (0.31) | — | |
| SCHEMBL24446257 | 0.84 | — | — | |
| SCHEMBL9728211 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL5870085 | 0.74 | ARG1 (0.31) | — | |
| SCHEMBL23115271 | 0.74 | POLB (0.30) | — | |
| SCHEMBL28875199 | 0.74 | — | — | |
| SCHEMBL10876264 | 0.73 | — | — | |
| SCHEMBL8701041 | 0.72 | — | — | |
| SCHEMBL5498766 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016550-A1 | Methods for Site-Specific Pegylation | IPSEN PHARMA S.A.S. (FR) | 2010-01-21 | — | — | US | disclosed |
| EP-2021397-A2 | METHODS FOR SITE-SPECIFIC PEGYLATION | Société de Conseils de Recherches et d'Applications Scientifiques, S.A.S. (FR) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007139997-A2 | METHODS FOR SITE-SPECIFIC PEGYLATION | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2007-12-06 | — | — | WO | disclosed |
| US-4775675-A | Thiazolidinecarboxylic acid derivatives and treatment of liver diseases therewith | BIOGAL GYOGYSZERGYAR (HU) | 1988-10-04 | — | — | US | disclosed |