SCHEMBL3486201

SCHEMBL3486201

COc1c(CC=C(C)C)c(=O)[nH]c2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.62
KDM4E B2RXH2 13/20 0.50
ALDH1A1 P00352 9/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HPGD P15428 6/20 0.48
PDE4D Q08499 1/20 0.46
HSD17B10 Q99714 7/20 0.46
GAA P10253 1/20 0.45
LMNA P02545 2/20 0.45
SLC2A1 P11166 1/20 0.44
VKORC1 Q9BQB6 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.42
CTSV O60911 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7693465 0.81 PPARG (0.68) PPARGKDM4EALDH1A1HPGDPDE4D
SCHEMBL29592568 0.74 PPARG (0.46) PPARGKDM4EALDH1A1HPGDPDE4D
SCHEMBL4065612 0.74 KDM4E (0.72) PPARGKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL11485415 0.74 PPARG (0.46) PPARGKDM4EALDH1A1SMN1; SMN2PDE4D
SCHEMBL31738389 0.72 KDM4E (0.59) PPARGKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL28165065 0.71 SLC2A1 (0.45) KDM4EALDH1A1HPGDHSD17B10GAA
SCHEMBL8542367 0.70 KDM4E (0.54) KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10
SCHEMBL6577224 0.70 KDM4E (0.66) KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10
SCHEMBL4540421 0.70 KDM4E (0.61) PPARGKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL6254132 0.70 MEN1 (0.40) PPARGKDM4EALDH1A1SMN1; SMN2SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1627565-A1 Use of flavanol derivatives for the cryopreservation of living cells Consejo Superior de Investigaciones Cientificas (CSIC) (ES) 2006-02-22 EP claimed
US-20250032448-A1 COMPOUND FOR USE IN THE TREATMENT AND/OR PREVENTION OF PARASITIC MEDIATED DISEASES KOH, Hwee Ling (SG) 2025-01-30 US disclosed
EP-2144618-B2 BIOEFFECTIVE KRILL OIL COMPOSITIONS AKER BIOMARINE ANTARCTIC AS (NO) 2024-11-20 EP disclosed
US-12144797-B2 Compound for use in the treatment and/or prevention of parasitic mediated diseases KOH, Hwee Ling (SG) 2024-11-19 US disclosed
CN-118599187-A Environment-friendly white carbon black dispersing agent and preparation method and application thereof 青州众瑞工贸有限公司 2024-09-06 CN disclosed
EP-3641826-B1 METHODS OF PRODUCING DRUG-CARRYING POLYMER SCAFFOLDS AND PROTEIN-POLYMER-DRUG CONJUGATES MERSANA THERAPEUTICS INC (US) 2023-12-06 EP disclosed
CN-116606548-A Preparation method of functionalized oligomeric PPO modified phthalonitrile resin 四川金象赛瑞化工股份有限公司 2023-08-18 CN disclosed
US-11540539-B2 Reduced sodium food products GENERAL MILLS, INC. (US) 2023-01-03 US disclosed
EP-3732994-B1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2022-11-09 EP disclosed
EP-3466930-B1 REDUCED SODIUM FOOD PRODUCT GEN MILLS INC (US) 2022-07-20 EP disclosed
WO-2014124216-A1 REDUCED SODIUM FOOD PRODUCT GENERAL MILLS, INC. (US) 2014-08-14 WO disclosed
WO-2014124220-A1 REDUCED SODIUM FOOD PRODUCT GENERAL MILLS, INC. (US) 2014-08-14 WO disclosed
WO-2014124209-A1 REDUCED SODIUM FOOD PRODUCTS GENERAL MILLS, INC. (US) 2014-08-14 WO disclosed
WO-2014124198-A1 REDUCED SODIUM FOOD PRODUCT GENERAL MILLS, INC. (US) 2014-08-14 WO disclosed
WO-2014124214-A1 REDUCED SODIUM FOOD PRODUCTS GENERAL MILLS, INC. (US) 2014-08-14 WO disclosed
WO-2014124205-A1 REDUCED SODIUM FOOD PRODUCTS GENERAL MILLS, INC. (US) 2014-08-14 WO disclosed
WO-2014124216-A1 REDUCED SODIUM FOOD PRODUCT GENERAL MILLS, INC. (US) 2014-08-14 WO disclosed
US-20100041612-A1 Fragments of the Glucagon-Like Peptide-1 and Uses Thereof NEW ENGLAND MEDICAL CENTER HOSPITALS, INC. 2010-02-18 US disclosed
US-6713072-B1 Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine CHIRON S.R.L. (IT) 2004-03-30 US disclosed
WO-2002026713-A1 ANTIPARASITIC COMPOUNDS KING'S COLLEGE LONDON (GB) 2002-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12144797-B2 Compound for use in the treatment and/or prevention of parasitic mediated diseases ICMT, ALG3, PFN1 PPARG 3999/4885KDM4E 2090/4885ALDH1A1 583/4885
US-20100041612-A1 Fragments of the Glucagon-Like Peptide-1 and Uses Thereof GLP1R, IAPP, GIPR PPARG 243/4885KDM4E 4687/4885ALDH1A1 4496/4885
US-20250032448-A1 COMPOUND FOR USE IN THE TREATMENT AND/OR PREVENTION OF PARASITIC MEDIATED DISEASES EPX, PKD2, MPO PPARG 2964/4885KDM4E 2625/4885ALDH1A1 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.