Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2304250 | 0.88 | KMT2A (0.49) | HSD11B1LMNAHSD17B10KMT2APOLB | |
| SCHEMBL18111957 | 0.86 | MAPT (0.47) | HSD11B1RAB9AMAPTNPC1TDP1 | |
| SCHEMBL1904599 | 0.86 | GRIN2D (0.51) | HSD11B1RAB9AMAPTTDP1SMN1; SMN2 | |
| SCHEMBL21447568 | 0.86 | HSD11B1 (0.52) | HSD11B1MAPTSMN1; SMN2CYP2C19MEN1 | |
| SCHEMBL3487498 | 0.85 | SRD5A2 (0.46) | HSD11B1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL13221587 | 0.85 | ALDH1A1 (0.46) | RAB9AMAPTNPC1TDP1SMN1; SMN2 | |
| SCHEMBL31294747 | 0.84 | HSD11B1 (0.41) | HSD11B1RAB9AMAPTNPC1TDP1 | |
| SCHEMBL1524169 | 0.84 | RAB9A (0.47) | RAB9AMAPTNPC1TDP1SMN1; SMN2 | |
| SCHEMBL3486362 | 0.83 | SMN1; SMN2 (0.43) | HSD11B1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL3486832 | 0.83 | CNR1 (0.47) | RAB9AMAPTNPC1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029619-A1 | FUSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMTED (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20100029619-A1 | FUSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMTED (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20100029619-A1 | FUSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMTED (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20100010235-A1 | Method of using rhodium quinonoid catalysts | BROWN UNIVERSITY | 2010-01-14 | — | — | US | disclosed |
| US-20100010235-A1 | Method of using rhodium quinonoid catalysts | BROWN UNIVERSITY | 2010-01-14 | — | — | US | disclosed |
| US-7569734-B2 | Method of using rhodium quinonoid catalysts | BROWN UNIVERSITY (US) | 2009-08-04 | — | — | US | disclosed |
| US-7569734-B2 | Method of using rhodium quinonoid catalysts | BROWN UNIVERSITY (US) | 2009-08-04 | — | — | US | disclosed |
| EP-2058309-A1 | FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-05-13 | — | — | EP | disclosed |
| EP-2058309-A1 | FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-05-13 | — | — | EP | disclosed |
| US-7495097-B2 | Rhodium quinonoid catalysts | BROWN UNIVERSITY (US) | 2009-02-24 | — | — | US | disclosed |
| US-7495097-B2 | Rhodium quinonoid catalysts | BROWN UNIVERSITY (US) | 2009-02-24 | — | — | US | disclosed |
| US-20070123715-A1 | Method of using rhodium quinonoid catalysts | BROWN UNIVERSITY | 2007-05-31 | — | — | US | disclosed |
| US-20070123715-A1 | Method of using rhodium quinonoid catalysts | BROWN UNIVERSITY | 2007-05-31 | — | — | US | disclosed |
| US-20070117981-A1 | Rhodium quinonoid catalysts | BROWN UNIVERSITY | 2007-05-24 | — | — | US | disclosed |
| US-20070117981-A1 | Rhodium quinonoid catalysts | BROWN UNIVERSITY | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117981-A1 | Rhodium quinonoid catalysts | NQO2, NDUFV2, QARS1 | HSD11B1 2040/4885RAB9A 167/4885MAPT 3897/4885 |
| US-20100029619-A1 | FUSED HETEROCYCLIC COMPOUND | IRAK1, IL1R1, IRAK2 | HSD11B1 693/4885RAB9A 2732/4885MAPT 3292/4885 |
| US-20100010235-A1 | Method of using rhodium quinonoid catalysts | NQO2, NQO1, RECQL | HSD11B1 1016/4885RAB9A 406/4885MAPT 4481/4885 |
| US-20070123715-A1 | Method of using rhodium quinonoid catalysts | NQO2, NQO1, RECQL | HSD11B1 1016/4885RAB9A 406/4885MAPT 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.