SCHEMBL454926

SCHEMBL454926

O=C(O)CC(N1C(=O)CCC1=O)S(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.41
ATM Q13315 1/20 0.41
ALDH1A1 P00352 1/20 0.37
PKM P14618 1/20 0.37
SLC1A2 P43004 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26623694 0.82 ALDH1A1 (0.35) KMT2AATMALDH1A1PKMSLC1A2
SCHEMBL27165392 0.80 KMT2A (0.34) KMT2AATMALDH1A1PKM
SCHEMBL9224514 0.75 KMT2A (0.40) KMT2AATMALDH1A1PKM
SCHEMBL3487387 0.75 KMT2A (0.44) KMT2AATMALDH1A1PKMSLC1A2
SCHEMBL3801263 0.74 KMT2A (0.46) KMT2AATMALDH1A1PKMSLC1A2
SCHEMBL4503936 0.74 KMT2A (0.36) KMT2AATMALDH1A1PKM
SCHEMBL28469683 0.73 KMT2A (0.38) KMT2AATM
SCHEMBL4261255 0.72 ALDH1A1 (0.42) KMT2AATMALDH1A1PKM
SCHEMBL4654434 0.71 ALDH1A1 (0.40) KMT2AATMALDH1A1PKMSLC1A2
SCHEMBL604671 0.71 ALDH1A1 (0.56) KMT2AATMALDH1A1PKMSLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 490 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4580694-A1 SEALANTS FOR TISSUE CLOSURE Ethicon, Inc. (US) 2025-07-09 EP claimed
WO-2024047443-A1 SEALANTS FOR TISSUE CLOSURE ETHICON, INC. (US) 2024-03-07 WO claimed
US-20240066178-A1 SEALANTS FOR TISSUE CLOSURE ETHICON, INC. (US) 2024-02-29 US claimed
US-20230310320-A1 SOLUBLE MICROCARRIER, METHOD FOR MANUFACTURING AND METHOD OF USE THEREOF NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) 2023-10-05 US claimed
US-10953073-B2 XTEN conjugate compositions and methods of making same AMUNIX PHARMACEUTICALS, INC. (US) 2021-03-23 US claimed
WO-2012162490-A1 NANOZYME COMPOSITIONS AND METHODS OF SYNTHESIS AND USE THEREOF BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2012-11-29 WO claimed
JP-4193917-B2 2008-12-10 JP claimed
EP-0832201-B1 A SAMPLE PRESENTATION APPARATUS FOR MASS SPECTROMETRY UNIV ARIZONA (US) 2005-10-05 EP claimed
US-20030149173-A1 Crosslinked polymer compositions and methods for their use RHEE WOONZA M (US) 2003-08-07 US claimed
US-20030143638-A1 Antibody/carrier complex, process for producing the same, method of controlling antigen-antibody reaction by using the same and immunoassay method MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-07-31 US claimed
US-20020013408-A1 Cross-linked polymer compositions and methods for their use ANGIODEVICE INTERNATIONAL GMBH (CH) 2002-01-31 US claimed
US-20010003126-A1 Method of making crosslinked polymer matrices in tissue treatment applications ANGIODEVICE INTERNATIONAL GMBH (CH) 2001-06-07 US claimed
US-6093541-A WITH METAL PRESENTATION SURFACE HAVING IMMOBILIZED COMPLEX OF TETHERING MOLECULE AND DIGESTION MOLECULE; FOR RAPID AND EFFICIENT ANALYSIS OF BIOMOLECULES USING MATRIX-ASSISTED LASER DESORPTION/IONIZATION TECHNIQUE ARIZONA STATE UNIVERSITY BOARD OF REGENTS (US) 2000-07-25 US claimed
JP-2000502380-A 2000-02-29 JP claimed
EP-0876165-A1 CROSSLINKED POLYMER COMPOSITIONS AND METHODS FOR THEIR USE COLLAGEN CORPORATION (US) 1998-11-11 EP claimed
WO-1997022371-A9 CROSSLINKED POLYMER COMPOSITIONS AND METHODS FOR THEIR USE 1997-09-04 WO claimed
WO-1997022371-A1 CROSSLINKED POLYMER COMPOSITIONS AND METHODS FOR THEIR USE COLLAGEN CORPORATION (US) 1997-06-26 WO claimed
US-12599624-B2 Biodegradable lung sealants ETHICON, INC. (US) 2026-04-14 US disclosed
EP-0359996-A2 Synthetic amino acid-and/or peptide-containing graft copolymers Al Marzook United Commercial Co. (KW) 1990-03-28 EP disclosed
US-4908404-A Water soluble high molecular weight cationic graft polymer BIOPOLYMERS, INC. (US) 1990-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12599624-B2 Biodegradable lung sealants CD44, TTPA, PLOD3 KMT2A 2895/4885ATM 326/4885ALDH1A1 678/4885
US-20030143638-A1 Antibody/carrier complex, process for producing the same, method of controlling antigen-antibody reaction by using the same and immunoassay method CD79B, CD99, PA2G4 KMT2A 2801/4885ATM 2400/4885ALDH1A1 3777/4885
US-10953073-B2 XTEN conjugate compositions and methods of making same XPA, TXLNA, NGLY1 KMT2A 2178/4885ATM 4398/4885ALDH1A1 3685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.