Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.61 |
| ▸ | CRHBP | P24387 | 3/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.54 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | NAT1 | P18440 | 1/20 | 0.49 |
| ▸ | MAX | P61244 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3487583 | 1.00 | S100A4 (0.61) | S100A4CRHBPCRHR2PTP4A3MGAM | |
| SCHEMBL13499566 | 1.00 | S100A4 (0.61) | S100A4CRHBPCRHR2PTP4A3MGAM | |
| SCHEMBL12902004 | 0.90 | S100A4 (0.61) | S100A4CRHBPCRHR2PTP4A3MGAM | |
| SCHEMBL6184140 | 0.90 | S100A4 (0.62) | S100A4CRHBPCRHR2MGAMGAA | |
| SCHEMBL6184142 | 0.90 | S100A4 (0.62) | S100A4CRHBPCRHR2MGAMGAA | |
| SCHEMBL12892070 | 0.90 | S100A4 (0.62) | S100A4CRHBPCRHR2MGAMGAA | |
| SCHEMBL13499588 | 0.82 | CRHBP (0.70) | S100A4CRHBPCRHR2PTP4A3MGAM | |
| SCHEMBL16453650 | 0.80 | PIM1 (0.62) | CRHBPCRHR2PTP4A3MGAMGAA | |
| SCHEMBL13499587 | 0.79 | CRHBP (0.62) | S100A4CRHBPCRHR2PTP4A3MGAM | |
| SCHEMBL13499569 | 0.78 | S100A4 (0.56) | S100A4CRHBPCRHR2PTP4A3MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431376-B2 | Bacterial replication systems and methods | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100028862-A1 | BACTERIAL REPLICATION SYSTEMS AND METHODS | Replidyne,Inc. (US) | 2010-02-04 | — | — | US | disclosed |
| EP-1759008-A4 | BACTERIAL REPLICATION SYSTEMS AND METHODS | REPLIDYNE INC (US) | 2008-08-06 | — | — | EP | disclosed |
| EP-1759008-A2 | BACTERIAL REPLICATION SYSTEMS AND METHODS | Replidyne, Inc. (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006071255-A9 | BACTERIAL REPLICATION SYSTEMS AND METHODS | REPLIDYNE INC (US) | 2007-02-15 | — | — | WO | disclosed |
| WO-2006071255-A2 | BACTERIAL REPLICATION SYSTEMS AND METHODS | REPLIDYNE, INC. (US) | 2006-07-06 | — | — | WO | disclosed |