Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.62 |
| ▸ | MGAM | O43451 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SI | P14410 | 1/20 | 0.58 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.58 |
| ▸ | S100A4 | P26447 | 1/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.54 |
| ▸ | PTP4A3 | O75365 | 4/20 | 0.54 |
| ▸ | GSK3B | P49841 | 3/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.50 |
| ▸ | NAT1 | P18440 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13499588 | 0.86 | CRHBP (0.70) | CRHBPCRHR2MGAMGAASI | |
| SCHEMBL10438698 | 0.84 | CRHBP (0.64) | CRHBPCRHR2MGAMGAASI | |
| SCHEMBL13499570 | 0.82 | MGAM (0.66) | CRHBPCRHR2MGAMGAASI | |
| SCHEMBL13499568 | 0.82 | GAA (0.62) | CRHBPCRHR2MGAMGAASI | |
| SCHEMBL13499577 | 0.81 | NAT1 (0.64) | CRHBPCRHR2GAAPTP4A3GSK3B | |
| SCHEMBL13499585 | 0.79 | CRHBP (0.56) | CRHBPCRHR2MGAMGAASI | |
| SCHEMBL3487584 | 0.79 | S100A4 (0.61) | CRHBPCRHR2MGAMGAASI | |
| SCHEMBL3487583 | 0.79 | S100A4 (0.61) | CRHBPCRHR2MGAMGAASI | |
| SCHEMBL13499566 | 0.79 | S100A4 (0.61) | CRHBPCRHR2MGAMGAASI | |
| SCHEMBL13499558 | 0.79 | PTP4A3 (0.71) | CRHBPCRHR2PTP4A3PIM1NAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431376-B2 | Bacterial replication systems and methods | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100028862-A1 | BACTERIAL REPLICATION SYSTEMS AND METHODS | Replidyne,Inc. (US) | 2010-02-04 | — | — | US | disclosed |