Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 3/20 | 0.70 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.70 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.70 |
| ▸ | PIM1 | P11309 | 1/20 | 0.61 |
| ▸ | MGAM | O43451 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | SI | P14410 | 1/20 | 0.59 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.59 |
| ▸ | NAT1 | P18440 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | S100A4 | P26447 | 1/20 | 0.55 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13499587 | 0.86 | CRHBP (0.62) | CRHBPCRHR2PTP4A3PIM1MGAM | |
| SCHEMBL10438698 | 0.85 | CRHBP (0.64) | CRHBPCRHR2PTP4A3PIM1MGAM | |
| SCHEMBL13499570 | 0.83 | MGAM (0.66) | CRHBPCRHR2PIM1MGAMGAA | |
| SCHEMBL28965550 | 0.82 | PTP4A3 (1.00) | CRHBPCRHR2PTP4A3PIM1MGAM | |
| SCHEMBL3487584 | 0.82 | S100A4 (0.61) | CRHBPCRHR2PTP4A3PIM1MGAM | |
| SCHEMBL3487583 | 0.82 | S100A4 (0.61) | CRHBPCRHR2PTP4A3PIM1MGAM | |
| SCHEMBL13499566 | 0.82 | S100A4 (0.61) | CRHBPCRHR2PTP4A3PIM1MGAM | |
| SCHEMBL6790831 | 0.81 | CRHBP (0.54) | CRHBPCRHR2PTP4A3PIM1MGAM | |
| SCHEMBL13499568 | 0.80 | GAA (0.62) | CRHBPCRHR2PTP4A3PIM1MGAM | |
| SCHEMBL13499585 | 0.80 | CRHBP (0.56) | CRHBPCRHR2PTP4A3MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431376-B2 | Bacterial replication systems and methods | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100028862-A1 | BACTERIAL REPLICATION SYSTEMS AND METHODS | Replidyne,Inc. (US) | 2010-02-04 | — | — | US | disclosed |