Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 10/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1532748 | 0.92 | FAAH (0.54) | FAAHMGLLPARP14OPRK1KCNH2 | |
| SCHEMBL1532764 | 0.88 | FAAH (0.49) | FAAHMGLLPARP14OPRK1KCNH2 | |
| SCHEMBL1532872 | 0.87 | FAAH (0.50) | FAAHMGLLPARP14OPRK1KCNH2 | |
| SCHEMBL1532848 | 0.86 | FAAH (0.61) | FAAHMGLLPARP14OPRK1KCNH2 | |
| SCHEMBL1532863 | 0.86 | FAAH (0.49) | FAAHMGLLPARP14OPRK1KCNH2 | |
| SCHEMBL1532795 | 0.86 | FAAH (0.52) | FAAHMGLLPARP14OPRK1KCNH2 | |
| SCHEMBL1532641 | 0.84 | MGLL (0.55) | FAAHMGLLPARP14OPRK1KCNH2 | |
| SCHEMBL1532788 | 0.82 | FAAH (0.50) | FAAHMGLL | |
| SCHEMBL12736163 | 0.79 | FAAH (0.49) | FAAH | |
| SCHEMBL12735950 | 0.79 | FAAH (0.50) | FAAHMGLLPARP14OPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009971-A1 | Pyridyl Non-Aromatic Nitrogen-Containing Heterocyclic-1-Carboxylate Compound | ASTELLAS PHARMA INC. (JP) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009971-A1 | Pyridyl Non-Aromatic Nitrogen-Containing Heterocyclic-1-Carboxylate Compound | FAAH, FAAH2, CNR1 | FAAH 1/4885MGLL 565/4885PARP14 1606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.