SCHEMBL348805

SCHEMBL348805

Cc1ccccc1N=C=S

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
CYP3A4 P08684 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
ALOX15 P16050 2/20 0.52
ABCB11 O95342 1/20 0.52
NR3C1 P04150 1/20 0.52
CYP1A2 P05177 1/20 0.52
ADRA2A P08913 1/20 0.52
ADORA3 P0DMS8 1/20 0.52
HPGD P15428 1/20 0.52
ADRA2C P18825 1/20 0.52
MAOA P21397 1/20 0.52
DRD1 P21728 1/20 0.52
SLC6A4 P31645 1/20 0.52
HTR2B P41595 1/20 0.52
CCR2 P41597 1/20 0.52
HSD17B10 Q99714 1/20 0.52
POLB P06746 1/20 0.47
MIF P14174 2/20 0.46
APLNR P35414 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29644492 1.00 ALDH1A1 (0.52) ALDH1A1CYP3A4TDP1ALOX15ABCB11
SCHEMBL8592479 0.88 ALDH1A1 (0.43) ALDH1A1CYP3A4TDP1ALOX15ABCB11
SCHEMBL9795474 0.82 ALDH1A1 (0.46) ALDH1A1CYP3A4TDP1ALOX15ABCB11
SCHEMBL944313 0.82 ALDH1A1 (0.48) ALDH1A1CYP3A4TDP1ALOX15ABCB11
SCHEMBL29374052 0.82 ALDH1A1 (0.62) ALDH1A1CYP3A4TDP1ALOX15ABCB11
SCHEMBL207554 0.82 ALDH1A1 (0.62) ALDH1A1CYP3A4TDP1ALOX15ABCB11
SCHEMBL2001200 0.80 ALDH1A1 (0.47) ALDH1A1CYP3A4TDP1ALOX15ABCB11
SCHEMBL437747 0.80 TSHR (0.47) ALDH1A1CYP3A4TDP1ALOX15HPGD
SCHEMBL29516244 0.80 TSHR (0.47) ALDH1A1CYP3A4TDP1ALOX15HPGD
SCHEMBL8675112 0.80 ACHE (0.37) ALDH1A1CYP3A4TDP1ALOX15ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 740 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12402638-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-09-02 US claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
US-12232516-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-02-25 US claimed
US-12193465-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-01-14 US claimed
CN-119080660-A Thiosemicarbazide menthyl formate compound, preparation method and application thereof 南京林业大学 2024-12-06 CN claimed
CN-114516848-B Preparation method of polycarbonate high-temperature degradation resistant agent and polycarbonate composition 万华化学集团股份有限公司 2024-02-02 CN claimed
CN-117247409-A 3-thio/seleno-phosphorylated imidazole derivative and synthetic method and application thereof 曲阜师范大学 2023-12-19 CN claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
US-9340518-B2 Process for the preparation of (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropdxy)benzylidene)-2-(propylimino)-3-(o-tolyl)thiazolidin-4-one and intermediate used in said process ACTELION PHARMACEUTICALS LTD. (CH) 2016-05-17 US claimed
CN-103864655-B A kind of synthetic method of dehydrogenation abietyl thiourea derivative GUANGXI UNIVERSITY (CN) 2015-12-30 CN claimed
US-20150203459-A1 PROCESS FOR THE PREPARATION OF [(2Z,5Z)-5-(3-CHLORO-4-((R)-2,3-DIHYDROXYPROPOXY)BENZYLIDENE)-2-(PROPYLIMINO)-3-](O-TOLYL)THIAZOLIDIN-4-ONE AND INTERMEDIATE USED IN SAID PROCESS ACTELION PHARMACEUTICALS, LTD. (CH) 2015-07-23 US claimed
EP-2885266-A1 PROCESS FOR THE PREPARATION OF!(2Z,5Z)-5-(3-CHLORO-4-((R)-2,3-DIHYDROXYPROPOXY)BENZYLIDENE)-2-(PROPYLIMINO)-3-!(O-TOLYL)THIAZOLIDIN-4-ONE AND INTERMEDIATE USED IN SAID PROCESS Actelion Pharmaceuticals Ltd. (CH) 2015-06-24 EP claimed
CN-104540800-A Process for the preparation of (2Z,5Z)-5-(3-chloro-4- ((R)-2,3-dihydroxypropoxy)benzylidene)-2-(propylimino)-3-(o-tolyl)thiazolidin-4-one and intermediate used in said process ACTELION PHARMACEUTICALS LTD 2015-04-22 CN claimed
CN-103864655-A Synthetic method of dehydroabietic acid group thiourea derivative UNIV GUANGXI 2014-06-18 CN claimed
WO-2014027330-A1 PROCESS FOR THE PREPARATION OF|(2Z,5Z)-5-(3-CHLORO-4-((R)-2,3-DIHYDROXYPROPOXY)BENZYLIDENE)-2-(PROPYLIMINO)-3-|(O-TOLYL)THIAZOLIDIN-4-ONE AND INTERMEDIATE USED IN SAID PROCESS ACTELION PHARMACEUTICALS LTD (CH) 2014-02-20 WO claimed
WO-2010065329-A2 NANOPARTICLES FOR CANCER TREATMENT THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-06-10 WO claimed
US-20060241178-A1 Compositions and methods for treating lung cancer IMMUNEGUARD LLC (US) 2006-10-26 US claimed
WO-2004060365-A1 COMPOSITIONS AND METHODS FOR TREATING LUNG CANCER AMERICAN HEALTH FOUNDATION (US) 2004-07-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150203459-A1 PROCESS FOR THE PREPARATION OF [(2Z,5Z)-5-(3-CHLORO-4-((R)-2,3-DIHYDROXYPROPOXY)BENZYLIDENE)-2-(PROPYLIMINO)-3-](O-TOLYL)THIAZOLIDIN-4-ONE AND INTERMEDIATE USED IN SAID PROCESS IL15, IL15RA, IL5 ALDH1A1 428/4885CYP3A4 76/4885TDP1 3308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.