Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.59 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2019142 | 0.92 | FTO (0.63) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL7976517 | 0.84 | FTO (0.40) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL21527330 | 0.82 | FTO (0.66) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL1539098 | 0.82 | FTO (0.81) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL984932 | 0.80 | FTO (0.66) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL29537895 | 0.80 | FTO (0.66) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL216815 | 0.78 | FTO (0.82) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL29564125 | 0.78 | FTO (0.82) | FTOMAPTMEN1KMT2AHPGD | |
| Fluorescein SCHEMBL3508466 | 0.78 | FTO (0.89) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL7030299 | 0.78 | FTO (0.53) | FTOMAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100080850-A1 | POLYPEPTIDE LIGANDS FOR TARGETING CARTILAGE AND METHODS OF USE THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE | 2010-04-01 | — | — | US | disclosed |
| US-7592009-B2 | Polypeptide ligands for targeting cartilage and methods of use thereof | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2009-09-22 | — | — | US | disclosed |
| EP-2084275-A2 | POLYPEPTIDE LIGANDS FOR TARGETING CARTILAGE AND METHODS OF USE THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008063291-A2 | POLYPEPTIDE LIGANDS FOR TARGETING CARTILAGE AND METHODS OF USE THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) | 2008-05-29 | — | — | WO | disclosed |
| US-20080118523-A1 | Chimeric polypeptide comprising tissue inhibitor of matrix metalloproteinases-3 (TIMP-3) for use in treatment and prevention of arthritic and degenerative joint disorders | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2008-05-22 | — | — | US | disclosed |
| US-20030082562-A1 | Maxam gilbert g/a sequence analysis by DHPLC | HORNBY DAVID P (GB) | 2003-05-01 | — | — | US | disclosed |
| EP-1274837-A2 | APPARATUS AND METHOD FOR SEPARATING AND PURIFYING POLYNUCLEOTIDES | TRANSGENOMIC, Inc. (US) | 2003-01-15 | — | — | EP | disclosed |
| US-20020137037-A1 | Method for DNA footprinting | TRANSGENOMIC, INC. | 2002-09-26 | — | — | US | disclosed |
| WO-2002061130-A2 | METHODS AND REAGENTS FOR ANALYSIS OF RNA STRUCTURE AND FUNCTION | TRANSGENOMIC, INC. (US) | 2002-08-08 | — | — | WO | disclosed |
| US-20020102563-A1 | Apparatus and method for separating and purifying polynucleotides | TRANSGENOMIC, INC. | 2002-08-01 | — | — | US | disclosed |
| US-20020094539-A1 | Methods and reagents for analysis of RNA structure and function | HORNBY DAVID P (GB) | 2002-07-18 | — | — | US | disclosed |
| US-20020086291-A1 | Methods and reagents for analysis of rna structure and function | TRANSGENOMIC, INC. | 2002-07-04 | — | — | US | disclosed |
| US-20020022224-A1 | Method for isolating single-stranded DNA | TRANSGENOMIC, INC. | 2002-02-21 | — | — | US | disclosed |
| WO-2001081566-A2 | APPARATUS AND METHOD FOR SEPARATING AND PURIFYING POLYNUCLEOTIDES | TRANSGENOMIC, INC. (US) | 2001-11-01 | — | — | WO | disclosed |
| EP-0294524-B1 | Real time scanning electrophoresis apparatus for DNA sequencing | PERKIN ELMER CORP (US) | 1997-11-26 | — | — | EP | disclosed |
| EP-0233053-B1 | Method of detecting electrophoretically separated oligonucleotides | APPLIED BIOSYSTEMS (US) | 1994-06-01 | — | — | EP | disclosed |
| US-4855225-A | LABELING WITH FLUORESCENT OR RHODANINE DYES | APPLIED BIOSYSTEMS, INC. (US) | 1989-08-08 | — | — | US | disclosed |
| US-4811218-A | Real time scanning electrophoresis apparatus for DNA sequencing | APPLIED BIOSYSTEMS, INC. (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0294524-A1 | Real time scanning electrophoresis apparatus for DNA sequencing | THE PERKIN-ELMER CORPORATION (US) | 1988-12-14 | — | — | EP | disclosed |
| EP-0233053-A2 | Method of detecting electrophoretically separated oligonucleotides | APPLIED BIOSYSTEMS, INC. (US) | 1987-08-19 | — | — | EP | disclosed |