SCHEMBL216815

SCHEMBL216815

Nc1ccc2c(c1)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.82
MAPT P10636 4/20 0.71
MEN1 O00255 4/20 0.71
KMT2A Q03164 4/20 0.71
HPGD P15428 2/20 0.71
HTT P42858 2/20 0.71
TDP1 Q9NUW8 2/20 0.71
CYP2C19 P33261 1/20 0.71
RECQL P46063 1/20 0.71
BLM P54132 1/20 0.71
SMAD3 P84022 1/20 0.71
PRMT1 Q99873 1/20 0.71
ACE2 Q9BYF1 1/20 0.71
ALDH1A1 P00352 3/20 0.50
ALOX12 P18054 2/20 0.50
ALOX15 P16050 2/20 0.50
HSD17B10 Q99714 2/20 0.50
CYP2C9 P11712 1/20 0.50
BRCA1 P38398 1/20 0.50
LMNA P02545 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29564125 1.00 FTO (0.82) FTOMAPTMEN1KMT2AHPGD
SCHEMBL6429118 0.95 FTO (0.75) FTOMAPTMEN1KMT2AHPGD
SCHEMBL29413057 0.90 FTO (1.00) FTOMAPTMEN1KMT2AHPGD
SCHEMBL220211 0.90 FTO (1.00) FTOMAPTMEN1KMT2AHPGD
SCHEMBL1539098 0.90 FTO (0.81) FTOMAPTMEN1KMT2AHPGD
SCHEMBL12203251 0.90 FTO (0.85) FTOMAPTMEN1KMT2AHPGD
SCHEMBL27920238 0.89 FTO (0.97) FTOMAPTMEN1KMT2AHPGD
Fluorescein SCHEMBL8697200 0.88 FTO (0.87) FTOMAPTMEN1KMT2AHPGD
SCHEMBL10900216 0.87 FTO (0.92) FTOMAPTMEN1KMT2AHPGD
SCHEMBL23352978 0.86 FTO (0.62) FTOMAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 463 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118518884-A Functionalized magnetic microsphere and application thereof in troponin immunodetection 山东交通学院 2024-08-20 CN claimed
CN-113117172-B Blood simulation medium and preparation method and application thereof 佛山市博新生物科技有限公司 2024-06-11 CN claimed
CN-115785117-B Compound, kit and application of compound serving as photomagnetic bimodal probe 北京大学第三医院(北京大学第三临床医学院) 2024-06-11 CN claimed
EP-3554526-B1 LUTEINIZING HORMONE-RELEASING HORMONE RECEPTOR (LHRH-R) CONJUGATES AND USES THEREOF PURDUE RESEARCH FOUNDATION (US) 2024-05-08 EP claimed
US-11883498-B2 Luteinizing hormone-releasing hormone receptor (LHRH-R) conjugates and uses thereof PURDUE RESEARCH FOUNDATION (US) 2024-01-30 US claimed
CN-114813689-B Method for analyzing absorption capacity of hyaluronic acid penetrating membrane 梅晔生物医药股份有限公司 2023-12-15 CN claimed
CN-116718644-A Carbon dioxide sensor material and device based on ion conduction gain effect 华南师范大学 2023-09-08 CN claimed
CN-115785117-A Compound, kit and application of compound and kit as photomagnetic bimodal probe 北京大学第三医院(北京大学第三临床医学院) 2023-03-14 CN claimed
CN-114813689-A Method for analyzing absorption capacity of hyaluronic acid penetrating cell membrane 梅晔生物医药股份有限公司 2022-07-29 CN claimed
CN-110643032-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2022-01-28 CN claimed
US-6812036-B2 DETECTING PREFERENTIAL COMPOUNDS IN CEREALS; OBTAIN CEREAL SAMPLE, MIX WITH TRACER, DETECT ADJUSTMENT IN FLUORESCENCE POLARIZATION, COMPARE TO CONTROL, MEASURE CONCENTRATION OF PREFERENTIAL PARTICLES DIACHEMIX LLC 2004-11-02 US claimed
US-20040214199-A1 Triphosphate oligonucleotide modification reagents and uses thereof AUDAX PRIVATE DEBT LLC, AS AGENT 2004-10-28 US claimed
EP-1320755-A2 FLUORESCENCE POLARIZATION-BASED HOMOGENEOUS ASSAY FOR DEOXYNIVALENOL DETERMINATION IN GRAINS Diachemix LLC (US) 2003-06-25 EP claimed
EP-1305327-A2 TRIPHOSPHATE OLIGONUCLEOTIDE MODIFICATION REAGENTS AND USES THEREOF Schwartz, David A. (US) 2003-05-02 EP claimed
US-20020055180-A1 Fluorescence polarization-based homogeneous assay for deoxynivalenol determination in grains DIACHEMIX LLC 2002-05-09 US claimed
WO-2002023196-A2 FLUORESCENCE POLARIZATION-BASED HOMOGENEOUS ASSAY FOR DEOXYNIVALENOL DETERMINATION IN GRAINS DIACHEMIX LLC (US) 2002-03-21 WO claimed
WO-2002010432-A2 TRIPHOSPHATE OLIGONUCLEOTIDE MODIFICATION REAGENTS AND USES THEREOF SCHWARTZ DAVID A (US) 2002-02-07 WO claimed
EP-0745602-A1 Quinidine immunoassay and reagents F. HOFFMANN-LA ROCHE AG (CH) 1996-12-04 EP claimed
EP-0371253-B1 Method and reagents for detecting amphetamine and/or d-methamphetamine in biological samples ABBOTT LAB (US) 1995-09-13 EP claimed
US-5099020-A Immunoassay with fluorescent compounds ABBOTT LABORATORIES (US) 1992-03-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040214199-A1 Triphosphate oligonucleotide modification reagents and uses thereof RNGTT, DUT, NUDT1 FTO 307/4885MAPT 4128/4885MEN1 4429/4885
US-11883498-B2 Luteinizing hormone-releasing hormone receptor (LHRH-R) conjugates and uses thereof GNRHR, LHCGR, GHRHR FTO 2148/4885MAPT 2652/4885MEN1 324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.