SCHEMBL3489558

SCHEMBL3489558

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nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
PDE4A P27815 1/20 0.36
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.34
NFKB1 P19838 1/20 0.34
PTGS2 P35354 1/20 0.34
THPO P40225 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TSHR P16473 2/20 0.33
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23933730 1.00 ALDH1A1 (0.39) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL1311637 1.00 ALDH1A1 (0.39) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL7156151 1.00 ALDH1A1 (0.39) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL15547653 1.00 ALDH1A1 (0.39) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL9075213 1.00 ALDH1A1 (0.39) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL28992556 0.94 ALDH1A1 (0.37) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL7153508 0.85 ALDH1A1 (0.34) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL3513773 0.85 ALDH1A1 (0.34) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL3344516 0.85 ALDH1A1 (0.34) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL28900822 0.85 ALDH1A1 (0.34) ALDH1A1PDE4AKDM4EMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150238596-A1 BIOCONJUGATES COMPRISING MODIFIED ANTIGENS AND USES THEREOF GLYCOVAXYN AG (CH) 2015-08-27 US disclosed
EP-2892566-A1 BIOCONJUGATES COMPRISING MODIFIED ANTIGENS AND USES THEREOF Glycovaxyn AG (CH) 2015-07-15 EP disclosed
WO-2014037585-A1 BIOCONJUGATES COMPRISING MODIFIED ANTIGENS AND USES THEREOF GLYCOVAXYN AG (CH) 2014-03-13 WO disclosed
EP-1509607-B1 IMMUNOGENIC SEQUENCES SECR DEFENCE (GB) 2013-02-20 EP disclosed
US-8198430-B2 Immunogenic sequences THE SECRETARY OF STATE FOR DEFENCE (GB) 2012-06-12 US disclosed
US-20100080828-A1 IMMUNOGENIC SEQUENCES THE SECRETARY OF STATE OF DEFENCE (GB) 2010-04-01 US disclosed
US-20070128225-A1 Immunogenic sequences PRIOR JOANN L 2007-06-07 US disclosed
US-20050112141-A1 Compositions and methods for treatment of neoplastic disease GRANDVIEW, LLC 2005-05-26 US disclosed
EP-1509607-A1 IMMUNOGENIC SEQUENCES The Secretary of State for Defence (GB) 2005-03-02 EP disclosed
US-20040214783-A1 conjugates, fusion proteins or naked nucleic acids of superantigen (SAg) which produce an anti-tumor responses in transfected host cells (tumor cells, accessory cells or lymphocytes); cancer treatment TERMAN DAVID S (US) 2004-10-28 US disclosed
WO-2003102191-A1 IMMUNOGENIC SEQUENCES THE SECRETARY OF STATE FOR DEFENCE (GB) 2003-12-11 WO disclosed
US-20030157113-A1 Mammalian cell which inhibits cellular activation by receptors specific for lipid-based tumor associatiated antigens; anticancer agents TERMAN DAVID S (US) 2003-08-21 US disclosed
US-20020177551-A1 Compositions and methods for treatment of neoplastic disease TERMAN DAVID S (US) 2002-11-28 US disclosed
US-4818817-A DEMULSIFICATION PETROLEUM FERMENTATIONS N.V. (AN) 1989-04-04 US disclosed
US-4704360-A DEMULSIFIERS PETROLEUM FERMENTATIONS (AN) 1987-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150238596-A1 BIOCONJUGATES COMPRISING MODIFIED ANTIGENS AND USES THEREOF O60361, EEA1, SELE ALDH1A1 2570/4885PDE4A 4541/4885KDM4E 4624/4885
US-20040214783-A1 conjugates, fusion proteins or naked nucleic acids of superantigen (SAg) which produce an anti-tumor responses in transfected host cells (tumor cells, accessory cells or lymphocytes); cancer treatment GZMB, SON, SRRT ALDH1A1 4875/4885PDE4A 4182/4885KDM4E 4410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.