SCHEMBL15547653

SCHEMBL15547653

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nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
PDE4A P27815 1/20 0.36
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.34
NFKB1 P19838 1/20 0.34
PTGS2 P35354 1/20 0.34
THPO P40225 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TSHR P16473 2/20 0.33
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23933730 1.00 ALDH1A1 (0.39) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL1311637 1.00 ALDH1A1 (0.39) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL7156151 1.00 ALDH1A1 (0.39) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL9075213 1.00 ALDH1A1 (0.39) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL3489558 1.00 ALDH1A1 (0.39) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL28992556 0.94 ALDH1A1 (0.37) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL7153508 0.85 ALDH1A1 (0.34) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL3513773 0.85 ALDH1A1 (0.34) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL3344516 0.85 ALDH1A1 (0.34) ALDH1A1PDE4AKDM4EMAPTTHRB
SCHEMBL28900822 0.85 ALDH1A1 (0.34) ALDH1A1PDE4AKDM4EMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087718-A1 A MULTIVALENT SHIGELLA VACCINE AND METHODS OF MAKING AND USING THEREOF INSTITUT PASTEUR (FR) 2026-04-30 WO disclosed
US-20240024489-A1 PROTECTED DISACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF ZWITTERIONIC OLIGOSACCHARIDES, AND CONJUGATES THEREOF INSTITUT PASTEUR (FR) 2024-01-25 US disclosed
US-20230346902-A1 Shigella-Tetravalent (Shigella4V) Bioconjugate GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-11-02 US disclosed
EP-4247828-A1 PROTECTED DISACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF ZWITTERIONIC OLIGOSACCHARIDES, AND CONJUGATES THEREOF Institut Pasteur (FR) 2023-09-27 EP disclosed
EP-4168040-A1 SHIGELLA-TETRAVALENT (SHIGELLA4V) BIOCONJUGATE GlaxoSmithKline Biologicals S.A. (BE) 2023-04-26 EP disclosed
WO-2022106703-A1 PROTECTED DISACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF ZWITTERIONIC OLIGOSACCHARIDES, AND CONJUGATES THEREOF INSTITUT PASTEUR (FR) 2022-05-27 WO disclosed
WO-2021255684-A1 SHIGELLA-TETRAVALENT (SHIGELLA4V) BIOCONJUGATE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2021-12-23 WO disclosed
WO-2014013495-A1 MEMBRANE-TARGETING AMINOGLYCOSIDE-BASED CATIONIC AMPHIPHILES AND THERAPEUTIC USES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2014-01-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230346902-A1 Shigella-Tetravalent (Shigella4V) Bioconjugate SPIN4, PA2G4, VSIR ALDH1A1 4249/4885PDE4A 2771/4885KDM4E 2787/4885
US-20240024489-A1 PROTECTED DISACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF ZWITTERIONIC OLIGOSACCHARIDES, AND CONJUGATES THEREOF SI, DAD1, FUT5 ALDH1A1 3593/4885PDE4A 4085/4885KDM4E 4416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.