SCHEMBL3490748

SCHEMBL3490748

CN(C)c1ccc2cc([C]=O)ccc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 1/20 0.45
APP P05067 1/20 0.45
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PSMB5 P28074 1/20 0.38
EGFR P00533 2/20 0.37
HTR6 P50406 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NSD2 O96028 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SLC16A3 O15427 1/20 0.35
SNCA P37840 2/20 0.35
MAPT P10636 2/20 0.35
BRD1 O95696 1/20 0.34
BRPF1 P55201 1/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12566471 0.80 TERT (0.64) TERTAPPALDH1A1TSHRALOX15
SCHEMBL4022260 0.80 ASIC3 (0.33)
SCHEMBL194965 0.78 ALDH1A1 (0.58) APPALDH1A1TSHRALOX15HSD17B10
SCHEMBL9098668 0.77 IGLV6-57 (0.37) TERTAPPALDH1A1PSMB5KDM4E
SCHEMBL15112995 0.76 ALDH1A1 (0.48) TERTAPPALDH1A1TSHRHTT
SCHEMBL3202067 0.75 APP (0.43) TERTAPPALDH1A1NSD2NPSR1
SCHEMBL1039993 0.75 ALDH1A1 (0.48) ALDH1A1TSHRALOX15HSD17B10KDM4E
SCHEMBL3206051 0.74 APP (0.44) TERTAPPALDH1A1TSHRALOX15
SCHEMBL13486808 0.74 APP (0.40) TERTAPPALDH1A1TSHRALOX15
SCHEMBL13486859 0.73 MAPT (0.47) APPALDH1A1KDM4ESNCAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105017271-A Hypochlorous acid fluorescence ratio probe and application thereof UNIV SHANDONG 2015-11-04 CN claimed
US-8445291-B2 Method for detecting target substance, and tag, DNA, vector, probe and detection kit for use therewith NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) 2013-05-21 US claimed
US-20100075434-A1 Method for detecting target substance, and tag, DNA, vector, probe and detection kit for use therewith NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) 2010-03-25 US claimed
CN-106039282-A AROMATIC-CATIONIC PEPTIDES AND USES OF SAME 康奈尔大学 2016-10-26 CN disclosed
CN-105017271-A Hypochlorous acid fluorescence ratio probe and application thereof UNIV SHANDONG 2015-11-04 CN disclosed
CN-105017271-A Hypochlorous acid fluorescence ratio probe and application thereof UNIV SHANDONG 2015-11-04 CN disclosed
US-8445291-B2 Method for detecting target substance, and tag, DNA, vector, probe and detection kit for use therewith NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) 2013-05-21 US disclosed
US-20100075434-A1 Method for detecting target substance, and tag, DNA, vector, probe and detection kit for use therewith NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) 2010-03-25 US disclosed