Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24450556 | 1.00 | THRB (0.43) | THRBLMNAALDH1A1SIGMAR1TDP1 | |
| Hydrochloric Acid SCHEMBL29274396 | 0.98 | THRB (0.42) | THRBLMNAALDH1A1SIGMAR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL29274395 | 0.98 | THRB (0.42) | THRBLMNAALDH1A1SIGMAR1L3MBTL1 | |
| SCHEMBL8412941 | 0.84 | SIGMAR1 (0.46) | THRBLMNAALDH1A1SIGMAR1PLA2G1B | |
| SCHEMBL6370391 | 0.83 | THRB (0.42) | THRBSIGMAR1CYP1A2CYP2C9HPGD | |
| SCHEMBL7229021 | 0.82 | SIGMAR1 (0.33) | SIGMAR1PLA2G1BPLA2G2AL3MBTL1 | |
| SCHEMBL5824397 | 0.80 | PLA2G1B (0.34) | LMNASIGMAR1PLA2G1BPLA2G2AL3MBTL1 | |
| Glycerin SCHEMBL1548176 | 0.78 | LMNA (0.56) | THRBLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL29150911 | 0.78 | LMNA (0.36) | THRBLMNAALDH1A1TDP1MAPK1 | |
| SCHEMBL1446074 | 0.76 | SIGMAR1 (0.35) | SIGMAR1PLA2G1BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098541-A | Lipid nanoparticles for delivery of nucleic acids and related methods of use | 阿卡格拉医药公司 | 2023-11-21 | — | — | CN | disclosed |
| US-20100076055-A1 | Cationic Lipids and Uses Thereof | ABBOTT LABORATORIES (US) | 2010-03-25 | — | — | US | disclosed |
| US-20100055169-A1 | CATIONIC LIPIDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2010-03-04 | — | — | US | disclosed |
| WO-2009129387-A2 | CATIONIC LIPIDS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2009-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076055-A1 | Cationic Lipids and Uses Thereof | LIPA, SGMS2, SGMS1 | THRB 1633/4885LMNA 640/4885ALDH1A1 4724/4885 |
| US-20100055169-A1 | CATIONIC LIPIDS AND USES THEREOF | LIPA, SGMS2, SGMS1 | THRB 1633/4885LMNA 640/4885ALDH1A1 4724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.