Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MYC | P01106 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HAAO | P46952 | 1/20 | 0.36 |
| ▸ | LPO | P22079 | 2/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19438800 | 0.82 | NOTUM (0.49) | NOTUMMEN1ABCC4LMNAPKM | |
| Hydrochloric Acid SCHEMBL3263567 | 0.81 | NOTUM (0.44) | NOTUMLMNAKMT2AALDH1A1TDP1 | |
| SCHEMBL30774967 | 0.79 | NOTUM (0.54) | NOTUMLMNAALDH1A1KDM4E | |
| SCHEMBL8519956 | 0.79 | NOTUM (0.54) | NOTUMMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL3492700 | 0.78 | NOTUM (1.00) | NOTUMMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL3493724 | 0.74 | NOTUM (0.49) | NOTUMMEN1LMNAPKMKMT2A | |
| SCHEMBL5256619 | 0.74 | NOTUM (0.74) | NOTUMALDH1A1KDM4E | |
| SCHEMBL16244948 | 0.73 | NOTUM (0.51) | NOTUMLMNA | |
| SCHEMBL4562515 | 0.72 | NOTUM (0.55) | NOTUMMEN1KMT2AALDH1A1MYC | |
| SCHEMBL3261972 | 0.72 | NOTUM (0.46) | NOTUMALDH1A1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689047-B | Pharmaceutical combination for the treatment of cancer | 普莱萨格生命科学公司 | 2025-03-21 | — | — | CN | disclosed |
| US-20100121048-A1 | Cyclic Amine Compound and Use Thereof for the Prophylaxis or Treatment of Hypertension | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121048-A1 | Cyclic Amine Compound and Use Thereof for the Prophylaxis or Treatment of Hypertension | REN, AGTR1, AGTR2 | NOTUM 1289/4885MEN1 750/4885ABCC4 2401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.