Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL372275 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAOAMAOBEGFR | |
| SCHEMBL4173477 | 0.81 | TERT (0.42) | ALDH1A1TERTAPPKDM4EMAOA | |
| SCHEMBL3502484 | 0.78 | KDM4E (0.44) | ALDH1A1TERTAPPKDM4EPDE3B | |
| SCHEMBL12566471 | 0.77 | TERT (0.64) | ALDH1A1TERTAPPKDM4EEGFR | |
| SCHEMBL22372457 | 0.73 | ALDH1A1 (0.51) | ALDH1A1APPKDM4EEGFRMETAP1 | |
| SCHEMBL17080971 | 0.73 | TERT (0.42) | ALDH1A1TERTAPPKDM4EMAOB | |
| SCHEMBL7286859 | 0.72 | GSTP1 (0.55) | ALDH1A1KDM4EMAOAMAOBEGFR | |
| SCHEMBL2025835 | 0.71 | TERT (0.58) | ALDH1A1TERTAPPKDM4EEGFR | |
| SCHEMBL3085755 | 0.71 | GSK3B (0.56) | ALDH1A1KDM4EMAOAMAOBEGFR | |
| SCHEMBL29540906 | 0.71 | GSK3B (0.62) | ALDH1A1KDM4EMAOAMAOBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445291-B2 | Method for detecting target substance, and tag, DNA, vector, probe and detection kit for use therewith | NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) | 2013-05-21 | — | — | US | claimed |
| US-20230392186-A1 | METHOD AND DEVICE FOR DETECTING TRANSGLUTAMINASES | Technische Universität Darmstadt (DE) | 2023-12-07 | — | — | US | disclosed |
| EP-4286528-A1 | METHOD AND DEVICE FOR DETECTING TRANSGLUTAMINASES | Technische Universität Darmstadt (DE) | 2023-12-06 | — | — | EP | disclosed |
| US-20230303635-A1 | DIAGNOSTIC METHODS AND COMPOSITIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-09-28 | — | — | US | disclosed |
| EP-4200341-A1 | DIAGNOSTIC METHODS AND COMPOSITIONS | The Regents of the University of California (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040484-A1 | DIAGNOSTIC METHODS AND COMPOSITIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-02-24 | — | — | WO | disclosed |
| US-8445291-B2 | Method for detecting target substance, and tag, DNA, vector, probe and detection kit for use therewith | NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) | 2013-05-21 | — | — | US | disclosed |
| US-8440835-B2 | Environmentally sensitive fluorophores | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-14 | — | — | US | disclosed |
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100075434-A1 | Method for detecting target substance, and tag, DNA, vector, probe and detection kit for use therewith | NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20090035796-A1 | Enzyme sensors including environmentally sensitive or fluorescent labels and uses thereof | THE ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY | 2009-02-05 | — | — | US | disclosed |
| EP-1869206-A2 | ENZYME SENSORS INCLUDING ENVIRONMENTALLY SENSITIVE OR FLUORESCENT LABELS AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2007-12-26 | — | — | EP | disclosed |
| US-20060211075-A1 | Enzyme sensors including environmentally sensitive or fluorescent labels and uses thereof | THE ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY | 2006-09-21 | — | — | US | disclosed |
| WO-2006094116-A2 | ENZYME SENSORS INCLUDING ENVIRONMENTALLY SENSITIVE OR FLUORESCENT LABELS AND USES THEREOF | THE ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | PTMS, IK, PHAX | ALDH1A1 4233/4885TERT 2525/4885APP 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.