SCHEMBL372275

SCHEMBL372275

CN(C)c1ccc2c(c1)C(=O)NC2=O

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
PPOX P50336 1/20 0.50
KDM4E B2RXH2 2/20 0.46
GSK3B P49841 1/20 0.44
CYP3A4 P08684 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
HPGD P15428 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
EGFR P00533 1/20 0.42
MAOA P21397 6/20 0.42
MAOB P27338 6/20 0.42
GRM5 P41594 2/20 0.42
GLA P06280 1/20 0.41
PDGFRB P09619 1/20 0.41
JAK2 O60674 1/20 0.41
JAK1 P23458 1/20 0.41
JAK3 P52333 1/20 0.41
METAP1 P53582 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22372457 0.85 ALDH1A1 (0.51) ALDH1A1PPOXKDM4ECYP3A4TDP1
SCHEMBL22372429 0.85 ALDH1A1 (0.51) ALDH1A1PPOXKDM4ECYP3A4TDP1
SCHEMBL3494397 0.82 ALDH1A1 (0.44) ALDH1A1PPOXKDM4ECYP3A4TDP1
SCHEMBL26695996 0.78 ALDH1A1 (0.42) ALDH1A1PPOXKDM4EGSK3BCYP3A4
SCHEMBL3502484 0.76 KDM4E (0.44) ALDH1A1PPOXKDM4EHPGDHSD17B10
SCHEMBL10926086 0.76 ALDH1A1 (0.59) ALDH1A1KDM4ECYP3A4TDP1HPGD
SCHEMBL9514250 0.76 ALDH1A1 (0.59) ALDH1A1KDM4ECYP3A4TDP1HPGD
SCHEMBL9769393 0.76 ALDH1A1 (0.59) ALDH1A1KDM4ECYP3A4TDP1HPGD
SCHEMBL1567332 0.75 ALDH1A1 (0.53) ALDH1A1KDM4ECYP3A4TDP1HPGD
Phthalimide SCHEMBL28091497 0.75 GSK3B (0.62) ALDH1A1GSK3BCYP3A4TDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12504375-B2 Method for monitoring and control of a wastewater process stream ECOLAB USA INC. (US) 2025-12-23 US claimed
US-20240044794-A1 Method for Monitoring and Control of a Wastewater Process Stream NALCO COMPANY LLC 2024-02-08 US claimed
US-20190204224-A1 Method for Monitoring and Control of a Wastewater Process Stream ECOLAB USA INC. (US) 2019-07-04 US claimed
US-20160245757-A1 A Method of Controlling Hydrophobic Contaminants by Utilizing a Fluorescent Dye ECOLAB USA INC. (US) 2016-08-25 US claimed
EP-3049807-A1 A METHOD OF CONTROLLING HYDROPHOBIC CONTAMINANTS BY UTILIZING A FLUORESCENT DYE Ecolab USA Inc. (US) 2016-08-03 EP claimed
WO-2015048241-A1 A METHOD OF CONTROLLING HYDROPHOBIC CONTAMINANTS BY UTILIZING A FLUORESCENT DYE ECOLAB USA INC. (US) 2015-04-02 WO claimed
EP-2409147-B1 USE OF HYDROPHOBIC DYES TO MONITOR HYDROPHOBIC CONTAMINANTS IN A PAPERMAKING PROCESS NALCO CO (US) 2014-07-30 EP claimed
US-8445291-B2 Method for detecting target substance, and tag, DNA, vector, probe and detection kit for use therewith NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) 2013-05-21 US claimed
EP-2409147-A1 USE OF HYDROPHOBIC DYES TO MONITOR HYDROPHOBIC CONTAMINANTS IN A PAPERMAKING PROCESS Nalco Company (US) 2012-01-25 EP claimed
WO-2010107725-A1 USE OF HYDROPHOBIC DYES TO MONITOR HYDROPHOBIC CONTAMINANTS IN A PAPERMAKING PROCESS NALCO COMPANY (US) 2010-09-23 WO claimed
US-20100075434-A1 Method for detecting target substance, and tag, DNA, vector, probe and detection kit for use therewith NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) 2010-03-25 US claimed
US-20090260767-A1 USE OF HYDROPHOBIC DYES TO MONITOR HYDROPHOBIC CONTAMINANTS IN A PAPERMAKING PROCESS EVERY PENNY COUNTS, INC. (US) 2009-10-22 US claimed
US-20260056107-A1 OPTICAL SYSTEMS AND PLATFORMS FOR SIMULTANEOUSLY ANALYZING MULTIPLE SOLUTION PROPERTIES UNIV CALIFORNIA (US) 2026-02-26 US disclosed
US-12504375-B2 Method for monitoring and control of a wastewater process stream ECOLAB USA INC. (US) 2025-12-23 US disclosed
US-12392782-B2 Characterization of protein binding to per- and polyfluoroalkyl substances NORTH CAROLINA STATE UNIVERSITY (US) 2025-08-19 US disclosed
EP-3866750-B1 SUSPENSION FORMULATIONS OF HIGH LOAD DISPERSIONS AUSTIN RES LABS CORP (US) 2025-06-18 EP disclosed
WO-2008106104-A2 ENVIRONMENTALLY SENSITIVE FLUOROPHORES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-09-04 WO disclosed
US-20080206885-A1 Environmentally sensitive fluorophores MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2008-08-28 US disclosed
US-20060234206-A1 Fluorescent probes for biological studies MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2006-10-19 US disclosed
US-4144072-A CONTAINING A PHTHALAZINONE AND A PHTHALIMIDE FUJI PHOTO FILM CO., LTD. (JP) 1979-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080206885-A1 Environmentally sensitive fluorophores ARFGEF1, TFEB, ARF5 ALDH1A1 170/4885PPOX 372/4885KDM4E 1262/4885
US-20060234206-A1 Fluorescent probes for biological studies FABP1, FABP3, FABP2 ALDH1A1 1342/4885PPOX 2101/4885KDM4E 4826/4885
US-20260056107-A1 OPTICAL SYSTEMS AND PLATFORMS FOR SIMULTANEOUSLY ANALYZING MULTIPLE SOLUTION PROPERTIES KIF11, HTT, NSF ALDH1A1 3401/4885PPOX 4488/4885KDM4E 4365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.