Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 6/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | TK1 | P04183 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Doxribtimine SCHEMBL3186020 | 0.88 | TK1 (0.56) | TK1 | |
| Thymidine Monophosphate SCHEMBL18785041 | 0.87 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL7876022 | 0.87 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL16092807 | 0.87 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL16280929 | 0.87 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL2037921 | 0.87 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL8366987 | 0.87 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL21257 | 0.87 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL3984895 | 0.87 | POLB (0.80) | TYMSPOLBTK1 | |
| Thymidine Monophosphate SCHEMBL29463974 | 0.87 | POLB (0.80) | TYMSPOLBTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2317857-B1 | USE OF TETRAKIS(N-ALKYLPYRIDINIUM)-PORPHYRIN DERIVATIVES FOR KILLING MICROBES OR PREVENTING THEIR GROWTH | FRONTIER SCIENT INC (US) | 2016-12-28 | — | — | EP | disclosed |
| US-8859760-B2 | Compositions for killing or preventing the growth of microbes | FRONTIER SCIENTIFIC, INC. (US) | 2014-10-14 | — | — | US | disclosed |
| US-20140179742-A1 | COMPOSITIONS FOR KILLING OR PREVENTING THE GROWTH OF MICROBES | FRONTIER SCIENTIFIC, INC. (US) | 2014-06-26 | — | — | US | disclosed |
| US-8633311-B2 | Topical application of porphyrins for killing or preventing the growth of bacteria or fungi on a mammal | FRONTIER SCIENTIFIC, INC. (US) | 2014-01-21 | — | — | US | disclosed |
| US-20120016289-A1 | ARTICLES, COMPOSITIONS, AND METHODS FOR KILLING OR PREVENTING THE GROWTH OF MICROBES | FRONTIER SCIENTIFIC (US) | 2012-01-19 | — | — | US | disclosed |
| CN-102245027-A | Use of tetrakis (n-alkylpyridinium) -porphyrin derivatives for killing microbes or preventing growth | FRONTIER SCIENT INC | 2011-11-16 | — | — | CN | disclosed |
| EP-2317857-A1 | USE OF TETRAKIS (N-ALKYLPYRIDINIUM) -PORPHYRIN DERIVATIVES FOR KILLING MICROBES OR PREVENTING GROWTH | Frontier Scientific, Inc. (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010014728-A1 | USE OF TETRAKIS (N-ALKYLPYRIDINIUM) -PORPHYRIN DERIVATIVES FOR KILLING MICROBES OR PREVENTING GROWTH | FRONTIER SCIENTIFIC INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| EP-1641391-A4 | PORPHYRINS AND METALLOPORPHYRINS FOR INHIBITING HEME IRON UPTAKE | FRONTIER SCIENT INC (US) | 2007-05-30 | — | — | EP | disclosed |
| EP-1641391-A2 | PORPHYRINS AND METALLOPORPHYRINS FOR INHIBITING HEME IRON UPTAKE | Frontier Scientific, Inc. (US) | 2006-04-05 | — | — | EP | disclosed |
| US-7008937-B2 | Porphyrins and metalloporphyrins for inhibiting heme iron uptake | FRONTIER SCIENTIFIC, INC. (US) | 2006-03-07 | — | — | US | disclosed |
| WO-2004110377-A2 | PORPHYRINS AND METALLOPORPHYRINS FOR INHIBITING HEME IRON UPTAKE | FRONTIER SCIENTIFIC, INC. (US) | 2004-12-23 | — | — | WO | disclosed |
| US-20040254155-A1 | Porphyrins and metalloporphyrins for inhibiting heme iron uptake | FRONTIER SCIENTIFIC, INC. | 2004-12-16 | — | — | US | disclosed |
| US-6620805-B1 | Drug delivery of antihepatitis viricide to hepatocytes | YALE UNIVERSITY | 2003-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179742-A1 | COMPOSITIONS FOR KILLING OR PREVENTING THE GROWTH OF MICROBES | CLPP, LPO, MPO | TYMS 990/4885POLB 370/4885TK1 1052/4885 |
| US-20120016289-A1 | ARTICLES, COMPOSITIONS, AND METHODS FOR KILLING OR PREVENTING THE GROWTH OF MICROBES | MPO, CLPP, LPO | TYMS 1204/4885POLB 912/4885TK1 1735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.