SCHEMBL3497059

SCHEMBL3497059

O=C1C2C3CCC(O3)C2C(=O)N1c1cccc(F)c1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.50
MGLL Q99685 1/20 0.50
L3MBTL1 Q9Y468 3/20 0.49
ADCY2 Q08462 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
ATM Q13315 2/20 0.44
ALDH1A1 P00352 4/20 0.44
FADS1 O60427 1/20 0.44
ACHE P22303 1/20 0.43
LMNA P02545 2/20 0.42
GAA P10253 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
MAPT P10636 2/20 0.41
POLB P06746 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3191291 0.81 ALDH1A1 (0.49) L3MBTL1MEN1KMT2AALDH1A1GAA
SCHEMBL13989083 0.81 ALDH1A1 (0.49) L3MBTL1MEN1KMT2AALDH1A1GAA
SCHEMBL3190784 0.81 ALDH1A1 (0.49) L3MBTL1MEN1KMT2AALDH1A1GAA
SCHEMBL3190777 0.81 ALDH1A1 (0.49) L3MBTL1MEN1KMT2AALDH1A1GAA
SCHEMBL3493956 0.81 ALOX15 (0.56) MGLLL3MBTL1ADCY2MEN1KMT2A
SCHEMBL15836588 0.80 MEN1 (0.65) L3MBTL1MEN1KMT2AATMALDH1A1
SCHEMBL3495788 0.80 MEN1 (0.65) L3MBTL1MEN1KMT2AATMALDH1A1
SCHEMBL10038047 0.80 MEN1 (0.65) L3MBTL1MEN1KMT2AATMALDH1A1
SCHEMBL10613654 0.80 ATM (0.66) FAAHMGLLL3MBTL1ADCY2MEN1
SCHEMBL3193645 0.80 L3MBTL1 (0.47) L3MBTL1MEN1KMT2AALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100137294-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS GENETIC TECHNOLOGIES LIMITED (AU) 2010-06-03 US claimed
US-20100137294-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS GENETIC TECHNOLOGIES LIMITED (AU) 2010-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137294-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS PPP1R10, TASP1, PPP5C FAAH 2986/4885MGLL 2427/4885L3MBTL1 598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.