Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 10/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22577081 | 0.85 | KDM4E (0.61) | GABRA2GABRB2ALDH1A1KDM4EHPGD | |
| SCHEMBL3499130 | 0.83 | GABRA2 (0.62) | GABRA2GABRB2KDM4EPTGS2POLB | |
| SCHEMBL21033491 | 0.82 | KDM4E (0.55) | GABRA2GABRB2ALDH1A1KDM4EHPGD | |
| SCHEMBL3500124 | 0.81 | GRM5 (0.53) | GABRA2GABRB2GRM5SMN1; SMN2 | |
| SCHEMBL21639355 | 0.80 | ALDH1A1 (0.53) | GABRA2GABRB2ALDH1A1KDM4EHPGD | |
| SCHEMBL21688698 | 0.79 | KDM4E (0.64) | GABRA2GABRB2ALDH1A1KDM4EHPGD | |
| SCHEMBL21012007 | 0.79 | KDM4E (0.52) | GABRA2GABRB2ALDH1A1KDM4EHPGD | |
| SCHEMBL3500116 | 0.79 | GABRA2 (0.57) | GABRA2GABRB2ALDH1A1KDM4EHPGD | |
| SCHEMBL31035692 | 0.77 | KDM4E (0.61) | GABRA2GABRB2ALDH1A1KDM4EHPGD | |
| SCHEMBL21004926 | 0.77 | KDM4E (0.61) | GABRA2GABRB2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | GABRA2 317/4885GABRB2 169/4885ALDH1A1 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.