Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Methane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL4614990 | 0.95 | CA5A (0.60) | — | |
| Methane SCHEMBL27992990 | 0.95 | — | — | |
| SCHEMBL128169 | 0.94 | — | — | |
| SCHEMBL246838 | 0.94 | CA2 (0.58) | — | |
| SCHEMBL15109974 | 0.94 | — | — | |
| SCHEMBL105 | 0.94 | — | — | |
| SCHEMBL8596055 | 0.94 | CA2 (0.58) | — | |
| SCHEMBL25599 | 0.94 | CA2 (0.58) | — | |
| Methane SCHEMBL27285423 | 0.91 | CA2 (0.47) | — | |
| SCHEMBL20570964 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080286822-A1 | Systems and methods for detecting toxins in a sample | WOODS HOLE OCEANOGRAPHIC INSTITUTION (US) | 2008-11-20 | — | — | US | claimed |
| US-8729048-B2 | Methods and materials for assessing responsiveness to PARP inhibitors and platinating agents | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2014-05-20 | — | — | US | disclosed |
| US-20130224312-A1 | METHODS AND MATERIALS FOR ASSESSING RESPONSIVENESS TO PARP INHIBITORS AND PLATINATING AGENTS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2013-08-29 | — | — | US | disclosed |
| CN-103013587-A | Method for producing palm biodiesel | MALAYSIAN PALM OIL BOARD | 2013-04-03 | — | — | CN | disclosed |
| CN-1548502-B | Method for Synthesizing Biodiesel | MALAYSIAN PALM OIL BOARD | 2012-11-21 | — | — | CN | disclosed |
| CN-101330964-B | Mercury capture from gas mixtures containing mercury | GORE ENTERPRISE HOLDINGS INC | 2012-08-15 | — | — | CN | disclosed |
| US-20100130439-A1 | GENOMIC MUTATION INHIBITORS THAT INHIBIT Y FAMILY DNA POLYMERASES | DEFENSE THREAT REDUCTION AGENCY/BC | 2010-05-27 | — | — | US | disclosed |
| EP-2150622-A2 | SYSTEMS AND METHODS FOR DETECTING TOXINS IN A SAMPLE | Woods Hole Oceanographic Institution (US) | 2010-02-10 | — | — | EP | disclosed |
| CN-101522214-A | Methods and compositions for needle-free delivery of particles | TRINITY BIOSYSTEMS INC (US) | 2009-09-02 | — | — | CN | disclosed |
| WO-2009023056-A2 | SYSTEMS AND METHODS FOR DETECTING TOXINS IN A SAMPLE | WOODS HOLE OCEANOGRAPHIC INSTITUTION (US) | 2009-02-19 | — | — | WO | disclosed |
| CN-101330964-A | Mercury capture from gas mixtures containing mercury | GORE ENTERPRISE HOLDINGS INC (US) | 2008-12-24 | — | — | CN | disclosed |
| US-20080286822-A1 | Systems and methods for detecting toxins in a sample | WOODS HOLE OCEANOGRAPHIC INSTITUTION (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080288528-A1 | Systems and methods for detecting toxins in a sample | WOODS HOLE OCEANOGRAPHIC INSTITUTION | 2008-11-20 | — | — | US | disclosed |
| CN-1548502-A | Palm diesel oil with low pour point suitable for corresponding climatic countries | 马来西亚棕油局 | 2004-11-24 | — | — | CN | disclosed |
| CN-1300322-A | Novel gene combination capable of changing soybean oil quality and function | DU PONT (US) | 2001-06-20 | — | — | CN | disclosed |
| US-5925893-A | POLYESTERURETHANE IONOMER | FUJI XEROX CO., LTD. (JP) | 1999-07-20 | — | — | US | disclosed |
| CN-1135724-A | Process for producting anhydrous pourable sugar tenside powders | HENKEL KGAA (DE) | 1996-11-13 | — | — | CN | disclosed |
| CN-1047493-A | The method for preparing alkyl ethoxy carboxylate | PROCETER & GAMBLE CO (US) | 1990-12-05 | — | — | CN | disclosed |
| US-4225315-A | Triazinones from amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-09-30 | — | — | US | disclosed |
| US-4035242-A | Distillative purification of alkane sulfonic acids | PPG INDUSTRIES, INC. (US) | 1977-07-12 | — | — | US | disclosed |