Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 2/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 3/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498974 | 1.00 | YAP1 (0.53) | YAP1ITGB3ITGA2BACACBCACNA1B | |
| SCHEMBL3500202 | 0.95 | CACNA1B (0.56) | YAP1ITGB3ITGA2BACACBCACNA1B | |
| SCHEMBL3500200 | 0.95 | CACNA1B (0.56) | YAP1ITGB3ITGA2BACACBCACNA1B | |
| SCHEMBL3743749 | 0.88 | ITGB3 (0.48) | YAP1ITGB3ITGA2BACACBCACNA1B | |
| SCHEMBL3743755 | 0.88 | ITGB3 (0.48) | YAP1ITGB3ITGA2BACACBCACNA1B | |
| SCHEMBL7329334 | 0.86 | YAP1 (0.50) | YAP1ITGB3ITGA2BACACBHRH2 | |
| SCHEMBL7329340 | 0.86 | YAP1 (0.50) | YAP1ITGB3ITGA2BACACBHRH2 | |
| SCHEMBL3997218 | 0.86 | ITGB3 (0.62) | YAP1ITGB3ITGA2BCACNA1BHDAC8 | |
| SCHEMBL27964318 | 0.85 | ITGB3 (0.49) | YAP1ITGB3ITGA2BACACBCACNA1B | |
| SCHEMBL14343115 | 0.85 | ITGB3 (0.49) | YAP1ITGB3ITGA2BACACBCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | YAP1 1692/4885ITGB3 2792/4885ITGA2B 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.