Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498324 | 0.90 | MAPT (0.33) | ALDH1A1LMNAMAPTHTTNPSR1 | |
| SCHEMBL3499830 | 0.88 | L3MBTL1 (0.32) | ALDH1A1LMNAMAPTHTTNPSR1 | |
| SCHEMBL2974076 | 0.85 | ALDH1A1 (0.35) | ALDH1A1MEN1TSHRKMT2ALMNA | |
| SCHEMBL13222243 | 0.84 | ALDH1A1 (0.34) | ALDH1A1MEN1TSHRKMT2ALMNA | |
| SCHEMBL3501783 | 0.82 | SMN1; SMN2 (0.32) | ALDH1A1KMT2ALMNAMAPTHTT | |
| SCHEMBL3500902 | 0.82 | MAPT (0.34) | MEN1TSHRKMT2AMAPTNPSR1 | |
| SCHEMBL2969708 | 0.82 | ALDH1A1 (0.35) | ALDH1A1MEN1TSHRKMT2ALMNA | |
| SCHEMBL2668633 | 0.82 | ALDH1A1 (0.34) | ALDH1A1MEN1TSHRKMT2ALMNA | |
| SCHEMBL13204127 | 0.82 | ALDH1A1 (0.36) | ALDH1A1MEN1TSHRKMT2ALMNA | |
| SCHEMBL2969111 | 0.82 | ALDH1A1 (0.33) | ALDH1A1MEN1TSHRKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410087-B2 | Indole compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20100144702-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144702-A1 | INDOLE COMPOUND | GCKR, GPR119, SLC5A1 | ALDH1A1 376/4885MEN1 2138/4885TSHR 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.