Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylphenylsulfide SCHEMBL23878729 | 0.88 | ACHE (0.42) | ACHECYP1A2CYP2C19SMN1; SMN2POLB | |
| Methylphenylsulfide SCHEMBL27620440 | 0.80 | CA12 (0.55) | ACHESMN1; SMN2POLBMAPTHSD17B10 | |
| Methylphenylsulfide SCHEMBL21243317 | 0.80 | ACHE (0.50) | ACHECYP1A2CYP2C19SMN1; SMN2POLB | |
| Methylphenylsulfide SCHEMBL10938535 | 0.80 | ACHE (0.50) | ACHECYP1A2CYP2C19SMN1; SMN2POLB | |
| Methylphenylsulfide SCHEMBL8201617 | 0.78 | MEN1 (0.45) | CYP1A2CYP2C19SMN1; SMN2POLBMAPT | |
| Methylphenylsulfide SCHEMBL8189417 | 0.78 | ACHE (0.47) | ACHECYP1A2CYP2C19SMN1; SMN2POLB | |
| Methylphenylsulfide SCHEMBL20533389 | 0.78 | ACHE (0.44) | ACHECYP1A2CYP2C19SMN1; SMN2POLB | |
| Methylphenylsulfide SCHEMBL20511991 | 0.77 | ACHE (0.42) | ACHECYP1A2CYP2C19SMN1; SMN2POLB | |
| Metacresol SCHEMBL11749131 | 0.76 | ACHE (0.85) | ACHECYP1A2CYP2C19SMN1; SMN2HSD17B10 | |
| Metacresol SCHEMBL2535890 | 0.76 | ACHE (0.85) | ACHECYP1A2CYP2C19SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160241-A1 | NOVEL COMPOUND HAVING GPR54 AGONISTIC ACTIVITY | KYOTO UNIVERSITY (JP) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160241-A1 | NOVEL COMPOUND HAVING GPR54 AGONISTIC ACTIVITY | GPR52, GPR84, GPR4 | ACHE 1735/4885CYP1A2 1062/4885CYP2C19 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.