Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | PTPRB | P23467 | 1/20 | 0.58 |
| ▸ | PTPRE | P23469 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | RAB7A | P51149 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189546 | 0.88 | ALDH1A1 (0.53) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL3452996 | 0.87 | ALDH1A1 (0.60) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL15199361 | 0.85 | PTPRC (0.47) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL4055676 | 0.82 | ALDH1A1 (0.66) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL3761338 | 0.78 | HSD17B10 (0.67) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL3495630 | 0.78 | MAPT (0.67) | ALDH1A1MAPTKDM4EADORA1HPGD | |
| SCHEMBL6315716 | 0.78 | CXCR2 (0.54) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL4083980 | 0.78 | ANO1 (0.53) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL5741314 | 0.77 | PTPN1 (0.75) | PTPRCPTPN2PTPN1PTPRBPTPRE | |
| SCHEMBL135906 | 0.77 | TDP1 (0.50) | PTPRCPTPN2PTPN1PTPRBPTPRE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3736276-B1 | THIENOCYCLIC COMPOUND AND SYNTHESIS METHOD THEREFOR AND APPLICATION THEREOF | SHANGHAI YUYAO BIOTECH LTD (CN) | 2023-03-01 | — | — | EP | disclosed |
| US-9376452-B2 | Rab7 GTPase inhibitors and related methods of treatment | ST. UNM (US) | 2016-06-28 | — | — | US | disclosed |
| US-20140248268-A1 | Rab7 GTPase Inhibitors and Related Methods of Treatment | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2014-09-04 | — | — | US | disclosed |
| US-8765803-B1 | Rab7 GTPase inhibitors and related methods of treatment | STC.UNM (US) | 2014-07-01 | — | — | US | disclosed |
| US-20100160255-A1 | SPIRO-CYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| US-20100160255-A1 | SPIRO-CYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| US-20100160255-A1 | SPIRO-CYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-1911753-A1 | SPIRO-CYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-04-16 | — | — | EP | disclosed |
| EP-1911753-A1 | SPIRO-CYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140248268-A1 | Rab7 GTPase Inhibitors and Related Methods of Treatment | RAB7A, RAB5B, RAB1A | PTPRC 1065/4885PTPN2 1864/4885PTPN1 2280/4885 |
| US-20100160255-A1 | SPIRO-CYCLIC COMPOUND | ACACA, CPT1B, PC | PTPRC 2014/4885PTPN2 1427/4885PTPN1 839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.