Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL35005

C[N+](C)(C)CCCS(=O)(=O)O.O=C([O-])C(F)(F)F

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BBOX1 O75936 5/20 0.47
ACHE P22303 2/20 0.35
ENPP2 Q13822 3/20 0.35
APP P05067 1/20 0.33
FAAH O00519 3/20 0.31
CES2 O00748 2/20 0.31
ATR Q13535 1/20 0.31
CES1 P23141 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA1A P35348 1/20 0.31
MEN1 O00255 2/20 0.30
NFKB1 P19838 2/20 0.30
KMT2A Q03164 2/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
APEX1 P27695 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL34876 0.95 BBOX1 (0.41) BBOX1ACHEENPP2APPFAAH
SCHEMBL918430 0.82 BBOX1 (0.58) BBOX1ACHEENPP2APPMEN1
SCHEMBL34763 0.79 BBOX1 (0.61) BBOX1ACHEENPP2APPMEN1
Trifluoromethanesulfonic Acid SCHEMBL34541 0.79 BBOX1 (0.47) BBOX1ACHEENPP2APPMEN1
SCHEMBL34764 0.78 BBOX1 (0.54) BBOX1ACHEENPP2APPMEN1
Trifluoroacetic Acid SCHEMBL34258 0.78 FAAH (0.35) BBOX1APPFAAHCES2CES1
Trifluoromethanesulfonic Acid SCHEMBL34542 0.78 BBOX1 (0.41) BBOX1ACHEENPP2APPMEN1
Trifluoroacetic Acid SCHEMBL1981477 0.77 DNM1 (0.44) BBOX1ACHEFAAHCES2CES1
Trifluoroacetic Acid SCHEMBL34745 0.77 FAAH (0.44) FAAHCES2CES1
SCHEMBL34691 0.76 BBOX1 (0.50) BBOX1ACHEENPP2APPMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2473277-B1 PALLADIUM CATALYST SYSTEM COMPRISING ZWITTERION OR ACID-FUNCTIONALIZED IONIC LIQUID UNIV DENMARK TECH DTU (DK) 2019-07-03 EP disclosed
US-20170341067-A1 Palladium Catalyst System Comprising Zwitterion And/Or Acid-Functionalyzed Ionic Liquid UNIV DENMARK TECH DTU (DK) 2017-11-30 US disclosed
CN-102625731-B Comprise the palladium catalyst system of the ionic liquid of zwitter-ion and/or acid functionalization DANMARKS TEKNISKE UNIVERSITET (DK) 2016-04-06 CN disclosed
CN-102625731-A Palladium catalyst system comprising zwitterion and/or acid-functionalized ionic liquid TECHNICAL UNIVERISTY OF DENMARK 2012-08-01 CN disclosed
EP-2473277-A1 PALLADIUM CATALYST SYSTEM COMPRISING ZWITTERION AND/OR ACID-FUNCTIONALIZED IONIC LIQUID Technical University of Denmark (DK) 2012-07-11 EP disclosed
US-20110065950-A1 PALLADIUM CATALYST SYSTEM COMPRISING ZWITTERION AND/OR ACID-FUNCTIONALYZED IONIC LIQUID TECHNICAL UNIVERSITY OF DENMARK (DK) 2011-03-17 US disclosed
WO-2011026860-A1 PALLADIUM CATALYST SYSTEM COMPRISING ZWITTERION AND/OR ACID-FUNCTIONALIZED IONIC LIQUID TECHNICAL UNIVERISTY OF DENMARK (DK) 2011-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110065950-A1 PALLADIUM CATALYST SYSTEM COMPRISING ZWITTERION AND/OR ACID-FUNCTIONALYZED IONIC LIQUID PDCD2L, PCCA, PDK2 BBOX1 1023/4885ACHE 2932/4885ENPP2 2417/4885
US-20170341067-A1 Palladium Catalyst System Comprising Zwitterion And/Or Acid-Functionalyzed Ionic Liquid PDCD2L, PCCA, PDK2 BBOX1 1023/4885ACHE 2932/4885ENPP2 2417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.