SCHEMBL3500543

SCHEMBL3500543

O=C(O)[C@H](CCO)N1C(=O)CC1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
PKM P14618 1/20 0.43
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 1/20 0.42
MAPK1 P28482 2/20 0.42
KDM4E B2RXH2 1/20 0.42
TP53 P04637 1/20 0.42
GLA P06280 1/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
HPGD P15428 1/20 0.42
ALOX12 P18054 1/20 0.42
NFKB1 P19838 1/20 0.42
APEX1 P27695 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PPM1B O75688 1/20 0.41
MME P08473 1/20 0.39
FOLH1 Q04609 1/20 0.37
MEN1 O00255 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1226562 0.90 ALDH1A1 (0.54) ALDH1A1PKMCYP1A2CYP2C19MAPK1
SCHEMBL8740830 0.85 MME (0.51) ALDH1A1PKMCYP1A2CYP2C19MAPK1
SCHEMBL10409196 0.82 KMT2A (0.54) ALDH1A1PKMCYP1A2CYP2C19MAPK1
SCHEMBL1696968 0.80 GSR (0.44) ALDH1A1PKMCYP1A2CYP2C19MAPK1
Ethylene Glycol SCHEMBL29002151 0.80 ALDH1A1 (0.51) ALDH1A1PKMCYP1A2CYP2C19MAPK1
SCHEMBL1333228 0.76 ALDH1A1 (0.56) ALDH1A1PKMCYP1A2CYP2C19MAPK1
SCHEMBL631270 0.76 ALDH1A1 (0.56) ALDH1A1PKMCYP1A2CYP2C19MAPK1
SCHEMBL18741147 0.76 FOLH1 (0.46) ALDH1A1PKMCYP1A2CYP2C19MAPK1
SCHEMBL3825813 0.74 ALDH1A1 (0.37) ALDH1A1PKMCYP1A2CYP2C19MAPK1
SCHEMBL3500235 0.73 MME (0.46) ALDH1A1PKMCYP1A2CYP2C19MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3272225-B1 COMPOSITION FOR FEED ADDITIVE, AND ANIMAL FEED COMPOSITION CONTAINING SAME CJ CHEILJEDANG CORP (KR) 2021-03-03 EP disclosed
US-20180042267-A1 Composition for Feed Additive, and Animal Feed Composition Containing Same CJ CHEILJEDANG CORPORATION (KR) 2018-02-15 US disclosed
EP-3272225-A1 COMPOSITION FOR FEED ADDITIVE, AND ANIMAL FEED COMPOSITION CONTAINING SAME CJ Cheiljedang Corporation (KR) 2018-01-24 EP disclosed
CN-107404904-A Composition for feed addictive and the animal feed composition comprising it CJ第制糖株式会社 2017-11-28 CN disclosed
WO-2016148488-A1 COMPOSITION FOR FEED ADDITIVE, AND ANIMAL FEED COMPOSITION CONTAINING SAME 씨제이제일제당(주) 2016-09-22 WO disclosed
EP-2657345-B1 Enzymatic method of producing L-methionine from a precursor and methylmercaptan CJ CHEILJEDANG CORP (KR) 2016-09-07 EP disclosed
US-20150211034-A1 Microorganism Producing L-Methionine Precursor and Method of Producing L-Methionine and Organic Acid from the L-Methionine Precursor CJ CHEILJEDANG CORPORATION (KR) 2015-07-30 US disclosed
US-9029105-B2 Microorganism producing L-methionine precursor and method of producing L-methionine and organic acid from the L-methionine precursor CJ CHEILJEDANG CORPORATION (KR) 2015-05-12 US disclosed
EP-2657345-A1 Enzymatic method of producing L-methionine from a precursor and methylmercaptan CJ Cheiljedang Corporation (KR) 2013-10-30 EP disclosed
EP-2046968-B1 Microorganism producing l-methionine precursor and method of producing l-methionine and organic acid from the l-methionine precursor CJ CHEILJEDANG CORP (KR) 2013-09-11 EP disclosed
US-20130231503-A1 Microorganism producing L-methionine precursor and method of producing L-methionine and organic acid from the L-methionine precursor CJ CHEILJEDANG CORPORATION (KR) 2013-09-05 US disclosed
US-8426171-B2 Microorganism producing L-methionine precursor and method of producing L-methionine and organic acid from the L-methionine precursor CJ CHEILJEDANG CORPORATION (KR) 2013-04-23 US disclosed
US-20100184164-A1 Microorganism Producing L-Methionine Precursor And Method Of Producing L-Methionine And Organic Acid From The L-Methionine Precursor CJ CHEILJEDANG CORPORATION (KR) 2010-07-22 US disclosed
EP-2046968-A1 MICROORGANISM PRODUCING L-METHIONINE PRECURSOR AND METHOD OF PRODUCING L-METHIONINE AND ORGANIC ACID FROM THE L-METHIONINE PRECURSOR CJ Cheiljedang Corporation (KR) 2009-04-15 EP disclosed
WO-2008013432-A1 MICROORGANISM PRODUCING L-METHIONINE PRECURSOR AND METHOD OF PRODUCING L-METHIONINE AND ORGANIC ACID FROM THE L-METHIONINE PRECURSOR CJ CHEILJEDANG CORPORATION (KR) 2008-01-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130231503-A1 Microorganism producing L-methionine precursor and method of producing L-methionine and organic acid from the L-methionine precursor MTR, MAT2A, METAP1 ALDH1A1 344/4885PKM 795/4885CYP1A2 320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.