Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.54 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 2/20 | 0.49 |
| ▸ | F3 | P13726 | 2/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29696883 | 0.88 | KDM4E (0.58) | KDM4EALDH1A1POLBGAAGRIK1 | |
| SCHEMBL2310250 | 0.88 | F7 (0.63) | KDM4EALDH1A1POLBGAAGRIK1 | |
| SCHEMBL3500217 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1POLBGAADAO | |
| SCHEMBL3499567 | 0.80 | F7 (0.76) | KDM4EALDH1A1F7F3DAO | |
| SCHEMBL9249785 | 0.78 | DAO (0.63) | KDM4EALDH1A1POLBGAAF7 | |
| SCHEMBL31422913 | 0.78 | DAO (0.63) | KDM4EALDH1A1POLBGAAF7 | |
| SCHEMBL29415468 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1POLBGAAGRIK1 | |
| SCHEMBL2806050 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1POLBGAAGRIK1 | |
| SCHEMBL1367967 | 0.76 | DAO (0.65) | KDM4EALDH1A1POLBGAAF7 | |
| Hydrochloric Acid SCHEMBL7273927 | 0.76 | MMP2 (0.54) | KDM4EALDH1A1POLBGAADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | KDM4E 2059/4885ALDH1A1 3047/4885POLB 4658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.